Results 71 to 80 of about 3,363,257 (386)

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Chronic stress associated to contraceptives use on the progression of ligature-induced periodontitis in rats

Revista de Odontologia da UNESP
Introduction Contraceptives are widely used by women in much of the world. The stress associated with their use can lead adverse responses in the body.
Débora Prado MARTINS, Tereza Aparecida Delle Vedove SEMENOFF, Álvaro Henrique BORGES, Natalino Francisco da SILVA, Alex SEMENOFF-SEGUNDO   +4 more
doaj   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

Advanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa, Jiali Wang, Mengzhao Xun, Jessica M. Rosenholm, Wuqing Wang, Yilai Shu, Hongbo Zhang   +6 more
wiley   +1 more source

Alteraciones prenatales y conocimientos sobre riesgos biosociales en embarazadas adolescentes

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: el embarazo en edades cada vez más tempranas se está convirtiendo en un problema social y de salud pública de alcance mundial.Objetivo: caracterizar el conocimiento de las embarazadas adolescentes sobre los riesgos biosociales en la gestación
Mayde González Crúz, Mirna León Acebo, Mayra Lourdes Pérez Nápoles, Jorge Luis Pérez Manzano, Liudmila Aponte Ramirez   +4 more
doaj  

A Bayesian cohort component projection model to estimate adult populations at the subnational level in data-sparse settings [PDF]

arXiv, 2021
Accurate estimates of subnational populations are important for policy formulation and monitoring population health indicators. For example, estimates of the number of women of reproductive age are important to understand the population at risk to maternal mortality and unmet need for contraception.
arxiv  

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

Advanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li, Fang Ye, Yucheng Zheng, Jie Wang, Haoran Peng, Lili Zhu, Lili Chen, Tao Yu, Huan Ge, Jiaqi He, Binghao Zhang, Jiayun Wu, Zhiyi Zhang, Liangliang Jiang, Geng Chen, Ping Zhao, Ke Lan, Zhenjiang Zhao, Xuhong Qian, Ke Xu, Yang Du, Honglin Li   +21 more
wiley   +1 more source

Psychometric Properties of a Measure Assessing Attitudes and Norms as Determinants of Intention to Use Oral Contraceptives

Asian Nursing Research, 2015
Purpose: Asian immigrant and Asian American women are less likely to use oral contraceptives (OCs) and tend to rely on low-efficacy methods of contraception.
Jongwon Lee, PhD, RN, Mauricio Carvallo, PhD, Taehun Lee, PhD   +2 more
doaj   +1 more source

Fast geostatistical inference under positional uncertainty: Analysing DHS household survey data [PDF]

arXiv, 2022
Household survey data from the Demographic and Health Surveys (DHS) Program is published with GPS coordinates. However, almost all geostatistical analyses of such data ignore that the published GPS coordinates are randomly displaced (jittered). In this short report, we develop a geostatistical model that accounts for the positional uncertainty when ...
arxiv  

Estimation of the covariance matrix of random effects in longitudinal studies [PDF]

Annals of Statistics 2007, Vol. 35, No. 6, 2795-2814, 2008
Longitudinal studies are often conducted to explore the cohort and age effects in many scientific areas. The within cluster correlation structure plays a very important role in longitudinal data analysis. This is because not only can an estimator be improved by incorporating the within cluster correlation structure into the estimation procedure, but ...
arxiv   +1 more source

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du, Xu Liu, Jianghua Shen, Hailong Yuan, Hao Zhang, Gan Xi, Yujing Li, Yuhan Wang, Jiahe Zhang, Chaofan Yang, Pengfei Xu, Jiawan Wang, Fang Wang, Siqi Liu, Yanan Zhou, Qi Gu, Jingjing Lu, Tuo Wei, Zeyu Gao, Jingyi Zang, Jun Wang, Moshi Song   +21 more
wiley   +1 more source