Results 71 to 80 of about 1,571,650 (304)

Contraceptive decision-making in India [PDF]

open access: yes, 2023
Women’s contraceptive decision-making continues to be at an all-time low in both urban and rural areas.
Ojha, Manini, Babbar, Karan
core  

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Correlates of Choice of Contraceptive Methods in Pakistan [PDF]

open access: yes
Since 1965, contraceptive use rate has been slowly increasing in Pakistan. In 1984-85, contraceptive ever use rate was 11.8 percent and current use rate was 9.1 percent [Government of Pakistan (1986)].
Mansoor ul Hassan Bhatti
core  

An exploration of social determinants of health in relation to contraceptive use among young adults [PDF]

open access: yes, 2022
Background: Low and inconsistent contraceptive use in young adults leads to increased unintended pregnancies. Prior research primarily focused on individual-level influences such as contraceptive attitudes and beliefs, with little consideration of social
Bhochhibhoya, Shristi
core  

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

open access: yesAdvanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer   +17 more
wiley   +1 more source

Advances in Male Contraception: When Will the Novel Male Contraception be Available?

open access: yesThe World Journal of Men's Health
Many contraceptive methods have been developed over the years due to high demand. However, female contraceptive pills and devices do not work for all females due to health conditions and side effects.
Jongwon Kim   +4 more
doaj   +1 more source

New vistas in contraceptive technology

open access: yes, 2008
Population forecasts predict that by 2050, about 150 million women (and couples) of child-bearing age will need contraception, and many of them are likely to find their needs unmet, due to problems of access, availability, and acceptability of the ...
Townsend, John   +3 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Factors Affecting Contraceptive Use in Pakistan [PDF]

open access: yes
Using data from the Pakistan Demographic and Health Survey of 1990-91, this study examines the effect of selected socio-cultural and supply factors on contraceptive use as reported by married women of reproductive ages.
Karin Ringheim, Naushin Mahmood
core  

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy