Results 41 to 50 of about 29,934 (292)

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

Provisional Dynamic Hinged External Fixation Enables Arthroscopy‐Assisted Circular Frame Reconstruction of Complex Tibial Plateau Fractures

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To describe the surgical technique and early operative outcomes of using a provisional dynamic external fixator to facilitate arthroscopic‐assisted reduction of complex tibial plateau fractures. Methods Between 2014 and 2024, we conducted a retrospective single‐center case series of Schatzker IV‐VI tibial plateau fractures treated with ...
Ilan Y. Mitchnik, Uri Hazan, Mohammad Shalabi, Yaron Golzman, Najib Chacar, Yakov Odessky, Vitali Aranbitski, Yiftah Beer   +7 more
wiley   +1 more source

Asymptomatic Intravesical Migration of an Intrauterine Device Detected during Delivery

International Journal of Anatomy Radiology and Surgery, 2023
Intrauterine Contraceptive Devices (IUCD) are known to be associated with many complications; however, uterine perforation with migration into adjacent soft tissue is rarely observed.
Ankit Vyas, Alhad Mulkalwar, Kamlesh Singh, Sujata Patwardhan   +3 more
doaj   +1 more source

Improving post-partum family planning services provided by female community health volunteers in Nepal: a mixed methods study. [PDF]

, 2020
BACKGROUND: Family planning services in the post-partum period, termed post-partum family planning (PPFP) is critical to cover the unmet need for contraception, especially when institutional delivery rates have increased. However, the intention to choose
Arulkumaran, S, Dhital, R, Dotel, BR, Makins, A, Mishra, S, Pande, S, Rajbhandari, S, Subedi, S, Thapa, K, Tunnacliffe, E-A, Vaidya, S   +10 more
core   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Religiosity and Sexual Risk Behaviors Among Latina Adolescents: Trends from 1995 to 2008 [PDF]

, 2011
Purpose: The purpose of this study was to determine trends in the influence of religiosity on sexual activity of Latina adolescents in the United States from 1995 to 2008 and to determine if differences existed between the Mexican American and other ...
Contreras J, DuRant R, Eaton D, Edwards L, Eggleston E, Gloria A, Prothero S, Wolter K   +7 more
core   +2 more sources

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

A rare case of urinary bladder stone secondary to migrating Intra Uterine Device.

Bhutan Health Journal, 2019
Intrauterine contraceptive devices (IUCDs) is one of the most commonly used in Bhutan. IUCDs are effective, safe, cheap, and has minimal systemic side effects. One of the major but rare complications is perforation of uterus and migration into pelvic and
Sonam Jamtsho
doaj   +1 more source

Contraception use in Malta [PDF]

, 2012
Temporal surveys of family control methods being used within the Maltese setting carried out in the 1970's and 1990's had shown a definite shift towards the more effective methods of contraception.
Savona-Ventura, Charles
core  

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source