Results 41 to 50 of about 913,811 (312)

The Skin Reservoir Model: A Tool for Evaluating Microdialysis Sampling of Large Biomarkers from Human Skin

open access: yesActa Dermato-Venereologica, 2020
Microdialysis is a well-established technique for sampling of small molecules from the human skin, but larger molecules are more difficult to recover. Consequently, sampling feasibility must be evaluated before microdialysis is used in vivo.
Katrine Baumann   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Assessment of the Pharmacokinetics and Pharmacodynamics of Injectable Lidocaine and a Lidocaine-Impregnated Latex Band for Castration and Tail Docking in Lambs

open access: yesAnimals
The objectives of this study were to assess the pharmacokinetics and pharmacodynamics of the current standard-of-care for pain mitigation in lambs during castration and tail docking (injectable lidocaine) and assess the ability of Lidocaine-Loaded Bands (
Joseph A. Ross   +8 more
doaj   +1 more source

The Archaeology of Earth

open access: yesCurrent Swedish Archaeology, 2004
In this article, the author takes a closer look at mounds built of earth. The point of departure is that there is more to earth than building material.
Tejre Gansum
doaj   +1 more source

GENERAL PRINCIPLES OF CONTRACT LAW AND ADMINISTRATIVE CONTRACT

open access: yesSTED Journal, 2022
An administrative contract is a specific contract with a special legal regime, subjects and characteristics that classify it as an institute between private and public law.
Zoran Filipović
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Wading bird populations respond to fluctuating conditions in a sub-tropical estuary

open access: yesFrontiers in Conservation Science
Wading bird populations are a useful tool for monitoring the function of wetlands, which are increasingly under threat throughout the world. The Indian River Lagoon on Florida’s Atlantic coast, a diverse ecosystem supporting numerous threatened and ...
Eric D. Stolen   +7 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

THE CHARACTERISTICS OF REED LIGHTWEIGHT CLAY BRICKS AFTER DRYING PROCESS

open access: yesInternational Islamic University Malaysia Engineering Journal, 2020
The drying procedure is one of the basic stages in the brick making process, particularly when utilizing the extrusion framing technique. This stage decides the quality and amount of the brick samples.
Ghazwan Abdulsamad Salman Algburi
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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