The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The valuation effect and determinants of corporate contracting : a thesis presented in partial fulfillment of the requirements for a Master of Business Studies at Massey University, December 2002 [PDF]
This study examined abnormal stock market returns to equity holders around corporate contract announcement that were obtained from Dow Jones & Company, Inc. between January 1, 1990 and December 31, 2000.
Chen, Lijia
core
Targeted Employee Retention: Performance-Based and Job-Related Differences in Reported Reasons for Staying [PDF]
A content model of 12 retention factors is developed in the context of previous theory and research. Coding of open-ended responses from 24,829 employees in the leisure and hospitality industry lends support to the identified framework and reveals that ...
Allen +42 more
core +4 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Error Theory of Contract [PDF]
Many people have false beliefs about contract doctrine. That pervasive phenomenon has profound practical, theoretical, and normative implications that neither courts nor scholars have recognized.
Seligman, Matthew A.
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Contract is Not Promise; Contract is Consent [PDF]
In the 1980s, Charles Fried was right to focus on what was missing from both the “death of contract” and “law and economics” approaches to contract law: the internal morality of contract. But he focused on the wrong morality.
Barnett, Randy E
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
LEGAL REGULATION OF THE BUYER`S OBLIGATION FOR PRICE PAYMENT ACCORDING TO THE VIENNA CONVENTION ON CONTRACTS FOR THE INTERNATIONAL SALE OF GOODS WITH EMPHASIS TO ITS ORDERLINESS IN REPUBLIC OF MACEDONIA [PDF]
Contract of sale is a basic legal instrument of international trade and therefore has a major role not only in domestic but also in international commodity trade. The corpus rights and obligations represent the content of the sales contract.
Natalija Ivanova
doaj
The objective elements of a licensing contract that are significant include: the entitlement to use an invention protected by a patent granted to a licensee and the use of the invention by a licensee in the scope for which the licence was granted.
Małgorzata Sekuła-Leleno
doaj +1 more source

