Results 41 to 50 of about 2,155,394 (299)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Motor-traction Contracts system

open access: yesIzvestiya of Saratov University. Economics. Management. Law, 2008
In the article problems of the market relations influence on the forming of the motor-traction contracts system are analyzed. In the work it is concluded, that the majority of contracts, connected with freight, supplement each other and make interconnected system of contracts.
openaire   +1 more source

The foreign experience in training public procurement specialists on the example of the USA, Great Britain and China

open access: yesУправление, 2020
The article reveals the features of the training of specialists in public procurement in countries with different types of economies and forms of state power in terms of the training system, applied pedagogical forms, methods and tools.
V. A. Tsibikov
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Modeling and Numerical Analysis of Revenue Sharing Contract Based on the Stackelberge Game Theory [PDF]

open access: yesInternational Journal of Supply and Operations Management, 2015
Considered supply chain in this article consists of one vendor and multiple retailers where the vendor applies vendor managed inventory. Considering vendor as a leader and retailers as followers, Stackelberg game theory is applied for modeling and ...
Mohammad Saber Fallah Nezhad   +2 more
doaj   +2 more sources

Contracts for System Design

open access: yesFoundations and Trends® in Electronic Design Automation, 2018
Recently, contract-based design has been proposed as an “orthogonal” approach that complements system design methodologies proposed so far to cope with the complexity of system design. Contract-based design provides a rigorous scaffolding for verification, analysis, abstraction/refinement, and even synthesis.
Benveniste, Albert   +9 more
openaire   +3 more sources

INTERNATIONAL COMPETITIVE BIDDING AS AN EFFECTIVE FORM OF WORLD TRADE

open access: yesVestnik MGIMO-Universiteta, 2018
Book review: Alexander Zakharov, International competitive bidding in modern world economic relations. Moscow:MGIMO-University, 2017. 379 p.
L. M. Kapitsa
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On the Issue of Split of State and Municipal Procurement

open access: yesСибирское юридическое обозрение, 2019
The current legislation of the Russian Federation in the field of procurement for state and municipal needs is not perfect and has a number of gaps. The article deals with the problem of differentiation of illegal behavior of customers from justified in ...
S. M. Rukavishnikov
doaj   +1 more source

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