Results 41 to 50 of about 1,313,465 (304)

Revenue Sharing and Control Rights in Team Production: Theories and Evidence from Joint Ventures.* [PDF]

open access: yes, 2003
This paper presents a model of the joint venture that is grounded in the stylized facts we found from a sample of 200 joint venture contracts. The model incorporates the revenue-sharing contract into the incomplete contract frameworks of Grossman-Hart ...
Bai, Chong-En, Tao, Zhigang, Wu, Changqi
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Libertas contractus. Paolo Comitoli SJ on Freedom of Contract

open access: yesCzasopismo Prawno-Historyczne, 2021
The paper presents the results of research devoted to the concept of freedom of contract in the writings of an early modern Italian Jesuit, Paolo Comitoli.
Piotr Alexandrowicz
doaj   +1 more source

Some Problems With Contract as Promise [PDF]

open access: yes, 1992
The promise theory views the origin of contract in the making of a promise. This means that it views the creation of contracts as arising, in an important part, from the voluntary acts of promisors rather than from third parties like the State.
Barnett, Randy E
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Rawls’ Political Constructivism as a Judicial Heuristic: A Response to Professor Allen [PDF]

open access: yes, 1999
In her Dunwody Lecture, Professor Anita Allen insightfully calls our attention to the social contract tropes that pepper American case law. She claims that these tropes function ideologically, disguising politics, biases, and raw power in judicial ...
Feldman, Heidi Li
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A well-ordered society with publicly acknowledged principles - a re-interpretation of Rawlsian social contract [PDF]

open access: yes, 2010
John Rawls is arguably the most influential political philosopher of the twentieth century. In his most seminal books, A Theory of Justice (1971), Rawls claims that his aim is to ‘present a conception of justice which generalizes and carries to a higher ...
Wong, Baldwin
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The effectiveness of evolutionary governance in mega construction projects: a moderated mediation model of relational contract and transaction cost

open access: yesJournal of Civil Engineering and Management, 2019
Mega construction project governance is an evolutionary process characterized by high transaction costs and complex interrelationships. Based on transaction cost theory, relational contract theory and evolutionary governance theory, this study explored ...
Dedong Wang, Shaoze Fang, Hongwei Fu
doaj   +1 more source

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