Results 121 to 130 of about 157,910 (293)
Defense Contractor Profit [PDF]
This research seeks to achieve two objectives: 1) to provide a comprehensive survey of research related to defense contractor profitability, and 2) to conduct an updated analysis of such profitability.
Eilert, Clayton S.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optimisation of processes of logistics companies in tender placement of orders
The article considers the problem of the occurrence of implicit costs for logistics companies during the tender placement of orders using the example of courier services.
E. L. Tcai
doaj +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Knowledge Sharing and Group Pressure
Knowledge Sharing and Group ...
CONTRACTOR, NOSHIR, RUTA, CATALDO
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A new approach to assessing Malaysian contractor satisfaction levels [PDF]
The extent of poor project outcomes is a recurring issue for construction industries worldwide. One of the main causes of these and project failure seems to be the inability of contractors to provide a high level of service quality to the project team ...
Masrom, Md Asrul, Skitmore, Martin
core
TVET Graduates Involvement in the Malaysian Construction Industry: Contractors’ Perspective
In Malaysia, Technical and Vocational Education and Training (TVET) relate to educational programs that practice skills, and knowledge focuses on industry-relevant training and job readiness.
Muhammad Dhia Danial Khairuddin +3 more
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source

