Results 161 to 170 of about 106,416 (301)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Leading Change: The Collaborative Science and Adaptive Management Program

San Francisco Estuary and Watershed Science, 2013
Valerie Connor
doaj  

Publisher Correction: Ring-Augmented versus Non-Ring-Augmented One-Anastomosis Gastric Bypass as Revisional Surgery after Sleeve Gastrectomy: a Comparative Cohort Study. [PDF]

Obes Surg
Elmasry A, Sallam M, Abdelaziz MF, Abdelatyy A, Abdelgawad M, Sahali MS, Mohamed EE, Altabbaa H, Shamarka AE, Zidan MH.   +9 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

'Us and them': A realist interview study exploring how and why health system factors influence dentists' participation in state funded, contracted primary dental care for low-income populations in Ireland. [PDF]

PLoS One
Leavy P, Daly B, Ford J, Burke S.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Attaining sustainability by navigating challenges in the transition to sustainable buildings using Fermatean fuzzy AHP. [PDF]

Sci Rep
Ansari ZN, Malik MR, Qureshi KM, Al-Qahtani MM, Qureshi MRNM.   +4 more
europepmc   +1 more source

EFOG:Energy Facility Contractors Group

The Energy Facility Contractors Group (EFCG) is a volunteer organization composed of Department of Energy (DOE) contractors working together to improve the cost effectiveness of DOE operations by promoting, coordinating, and facilitating the active ...

core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Understanding the role of entropy in designing high-performance thermoelectrics. [PDF]

Sci Adv
Ghosh S, Kwon S, Li W, Mandal D, Nozariasbmarz A, Furton E, Ahn M, Karan SK, Beese AM, Xia Y, Priya S, Poudel B.   +11 more
europepmc   +1 more source