Results 231 to 240 of about 470,308 (293)

An intertwined triple-bottom-line rating system for highway sustainability in developing countries. [PDF]

Sci Rep
Rageh MO, Elbeltagi EE, Gabr AR, El-Badawy SM, Motawa IA.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Understanding homeowner decision-making through demographics: Barriers to housing retrofit at scale. [PDF]

PLoS One
Panakaduwa C, Coates P, Munir M.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Policy innovation of construction waste management in Xi'an, China: A SWOT analysis of incentive mechanisms. [PDF]

PLoS One
Liu H, Yang S, Jusoh MNH.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Creating an integrated innovation system to enable the adaptation and uptake of health-system innovations in Canada: insights from citizen panels and a national stakeholder dialogue. [PDF]

Health Res Policy Syst
Bhuiya AR, DeMaio P, Cura JD, Gauvin FP, Hagens S, Hébert P, Lavis JN, McMurray J, Moat KA, Reid RJ, Sveistrup H, Tamblyn-Watts L, Wilson MG.   +12 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Adapting the CIERA framework to assess road infrastructure resilience to climate-related events. [PDF]

Jamba
Doomah Z.
europepmc   +1 more source

Erratum: Diabetes and Acute Care Use Among Patients With Metastatic Prostate Cancer Treated With Androgen Receptor Signaling Inhibitors. [PDF]

JCO Oncol Pract
Liu MA, Raghunathan R, Runcie K, Wang S, Wright JD, Wei AZ, Stein M, Hershman DL.   +7 more
europepmc   +1 more source