Results 171 to 180 of about 1,724,251 (331)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Location of links in the pharmaceutical value chain in Сhina: the role of contract research organizations

, 2023
Natalia A. Volgina, Na Li
openalex   +2 more sources

Designing Thermally Compatible Template‐Coating Pairs Toward Dimensionally Stable 3D Porous Carbons with Tunable Density

Advanced Functional Materials, EarlyView.
3D porous carbons with tunable density are crucial for energy storage, separations, and load‐bearing applications; however, their fabrication is often constrained by shrinkage during pyrolysis. This study optimizes and demonstrates the versatility of a template–coating pair strategy, producing materials that largely retain their shape and hierarchical ...
Adarsh Suresh, Manuela Campos, Kendrick Xie, Elektra Makris, Jonah Lovejoy, Maya El Shamsy, Chong Liu, Stuart J Rowan   +7 more
wiley   +1 more source

Superpixel Contracted Graph-Based Learning for Hyperspectral Image Classification [PDF]

, 2020
Philip Sellars, Angelica I. Aviles-Rivero, Carola-Bibiane Schonlieb   +2 more
openalex   +1 more source

Financing Defense Contracts [PDF]

, 1964
Gubin, E. K.
core   +2 more sources

Multi‐Faceted Binder Enhancement via Slurry‐Applicable Thiol‐Ene Click Chemistry for Low‐Pressure‐Operable All‐Solid‐State Batteries

Advanced Functional Materials, EarlyView.
Cross‐linked binders with enhanced resiliencies under low operating pressures are designed via in situ thiol‐ene click reactions within slurries. Cross‐linking improves the Young's moduli and elasticities of the styrene‐butadiene rubber binders, effectively mitigating interparticle delamination within the composite cathodes induced by volumetric ...
Young Joon Park, Kyu Tae Kim, Seunggoo Jun, Jong Seok Kim, Jaehyun Yoon, Cheol Bak, Yong Min Lee, Dong Hyeon Kim, Ji Young Kim, Yoon Seok Jung   +9 more
wiley   +1 more source

Going beyond compliance to build on the Researcher Development Concordat. [PDF]

Elife
Drake RAR, Gray LA, Rogers C, Vandrey B, Chang J.   +4 more
europepmc   +1 more source

Securing smart contract with runtime validation [PDF]

, 2020
Ao Li, Jemin Andrew Choi, Fan Long
openalex   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source