Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Problematika nepomenovaných zmlúv v občianskom práve a ich uzatváranie s pohľadom de lege ferenda
One of the key branches of private law is the law of contractual obligations. In addition to innominate contracts, which are most often used in practice, a category of innominate contracts and a special category was created, the category of so-called ...
Erika Dubajová Javúreková
doaj +1 more source
Novation as a method of termination of obligations [PDF]
The paper presents an analysis of the issue of novation in contract law. Novation is a contract between the creditor and debtor in order to replace its existing obligation with a new one.
Perović Marko
doaj +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The role of a MAC clauses in mergers and acquisitions during economic uncertainty
In the era of many economic uncertainties that significantly strain the system of market forces, some enterprises have been forced to use mechanisms allowing to limit the impact of unfavorable financial parameters on their financial condition ...
Karol Partacz
doaj +1 more source
FY2017 Highway Construction Program Expenditures/Obligations [PDF]
This report describes the highway construction program, actual expenditures of the program and contractual obligations of the program for FY ...
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Contractual obligations analysis for construction waste management in Canada
Construction industry creates a massive amount of waste, which typically ends up in landfills. Canadian construction industry represents 30% of the total municipal solid waste deposited in landfills.
Daylath Mendis +2 more
doaj +1 more source
FY2014 Highway Construction Program Expenditures/Obligations [PDF]
This report describes the highway construction program, actual expenditures of the program and contractual obligations of the program for FY ...
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source

