Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez +4 more
wiley +1 more source
A systematic review of global COVID-19 vaccine PPPs: drivers and barriers to governance alignment. [PDF]
Qi X.
europepmc +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
Sustainable Health Care Public-Private Partnerships in Emerging Economies. [PDF]
Moro-Visconti R.
europepmc +1 more source
The Family Farm: Regulating Farm Act Avoidance Techniques Through Restrictions on Vertical Integration and Production Contracting [PDF]
Billings, Alan L.
core +2 more sources
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Integrative deep learning strategies to enhance early-stage drug discovery: optimizing computational structure-activity modeling for pharmacotherapeutic innovation. [PDF]
Rezazi S, Si-Moussa C, Hanini S.
europepmc +1 more source
Stable population movements as a factor of economic stabilization and integration of the Western Balkans into the European Union [PDF]
Grecic, Vladimir
core
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess +3 more
wiley +1 more source

