Results 211 to 220 of about 82,694 (258)

Identification of Urinary Exosomal microRNAs Associated With Subclinical Acute T‐Cell‐Mediated Rejection in Kidney Transplant Recipients

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT This study aimed to evaluate the diagnostic utility of urinary exosomal microRNAs (miRNAs) in subclinical rejection following kidney transplantation by comparing miRNA expression profiles in urinary exosomes between patients with no evidence of rejection and patients with subclinical T‐cell‐mediated rejection (sc‐TCMR), as confirmed by ...
Soichiro Tajima   +11 more
wiley   +1 more source

Real‐world treatment trajectories preceding GLP‐1 receptor agonist initiation in type 2 diabetes: A descriptive UK population‐based cohort study on adherence to national clinical guidelines

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3692-3702, May 2026.
Abstract Aims To investigate glucose‐lowering treatment trajectories preceding glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) initiation in UK primary care, while assessing alignment with contemporary UK clinical guidelines, considering calendar time, cardiovascular disease (CVD) history, and obesity status.
Franziska S. Ulrich   +3 more
wiley   +1 more source

Baseline and 4‐year associations between prediabetes and kidney impairment: Insights from the ILERVAS cohort

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3777-3787, May 2026.
Abstract Aims Prediabetes is a prevalent condition associated with increased cardiovascular and renal risk. However, the long‐term impact of haemoglobin A1c (HbA1c) within the range defined as prediabetes on kidney function remains unclear. This study aimed to evaluate the association between prediabetes and renal function (estimated glomerular ...
Aitziber Izarra   +23 more
wiley   +1 more source

Mineralocorticoid receptor antagonists: Efficacy and safety in chronic kidney disease

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3568-3581, May 2026.
Abstract The mineralocorticoid receptor (MR) has a multifaceted role in normal physiologic functions. However, research has uncovered the deleterious consequences of overactivation of the MR. It has been implicated in chronic kidney disease (CKD) via its strong association with glomerulosclerosis, interstitial fibrosis, proteinuria, and decline in ...
Amy K. Mottl   +2 more
wiley   +1 more source

Rapid improvement of renal microcirculatory homeostasis by liraglutide following diabetes induction

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4066-4081, May 2026.
Abstract Aims Renal microvascular dysfunction is a central driver of diabetic kidney disease, yet the potential for rapid therapeutic reversal remains obscure. We investigated the effect of short‐term liraglutide on early changes in the renal microcirculation post‐induction of diabetes.
Yuan Li   +8 more
wiley   +1 more source

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