Results 51 to 60 of about 935,562 (336)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Performance of Computed Tomography of the Kidneys, Ureter and Bladder in Non-Calculus Diagnoses: A Comparative Review of Non-Enhanced with Intravenous Contrast-Enhanced Imaging

Diagnostics
Background/Objectives: Non-enhanced computed tomography of the kidneys, ureters and bladder (NECT KUB) is the initial imaging modality for suspected nephroureterolithiasis. However, for alternative diagnoses, NECT may not be the ideal technique.
Alexander T. O’Mahony, Michael G. Waldron, David J. Ryan, Brian Carey, Sahil Shet, Eid Kakish, Patrick O'Regan, David Glynn, Josephine Barry, Owen J. O'Connor, Michael M. Maher   +10 more
doaj   +1 more source

Dynamic Contrast-Enhanced CT in Patients with Pancreatic Cancer

Diagnostics, 2016
The aim of this systematic review is to provide an overview of the use of Dynamic Contrast-enhanced Computed Tomography (DCE-CT) in patients with pancreatic cancer. This study was composed according to the PRISMA guidelines 2009.
Rie Ø. Eriksen, Louise S. Strauch, Michael Sandgaard, Thomas S. Kristensen, Michael B. Nielsen, Carsten A. Lauridsen   +5 more
doaj   +1 more source

Acute myocardial infarction on Nongated chest computed tomography

Radiology Case Reports, 2020
Contrast-enhanced chest computed tomography (CT) is not considered part of the evaluation of myocardial infarction. However, acute myocardial infarction has been detected on contrast-enhanced chest CT as areas of decreased myocardial enhancement in ...
Maria Salgado Guerrero, MD, Gabriela Cepeda De Jesus, MD, Wakil Irfan, MD, Geraldine Villasana Gomez, MD, Ana B. Arevalo, MD, Robert Faillace, MD   +5 more
doaj   +1 more source

Contrast-enhanced Dedicated Breast CT: Initial Clinical Experience [PDF]

Radiology, 2010
To quantify contrast material enhancement of breast lesions scanned with dedicated breast computed tomography (CT) and to compare their conspicuity with that at unenhanced breast CT and mammography.Approval of the institutional review board and the Radiation Use Committee and written informed consent were obtained for this HIPAA-compliant study ...
Nicolas D, Prionas, Karen K, Lindfors, Shonket, Ray, Shih-Ying, Huang, Laurel A, Beckett, Wayne L, Monsky, John M, Boone   +6 more
openaire   +2 more sources

Association between contrast enhancement on contrast‑enhanced CT and lenvatinib effectiveness in hepatocellular carcinoma

Molecular and Clinical Oncology, 2021
The aim of the present study was to investigate whether the degree of contrast enhancement on contrast-enhanced (CE)-CT can predict the prognosis of patients with hepatocellular carcinoma (HCC) treated with lenvatinib (LEN). A total of 67 consecutive patients with LEN-treated HCC were retrospectively analysed.
Okamura, Shusuke, Shimose, Shigeo, Niizeki, Takashi, Kamachi, Naoki, Noda, Yu, Shirono, Tomotake, Iwamoto, Hideki, Nakano, Masahito, Kuromatsu, Ryoko, Koga, Hironori, Torimura, Takuji   +10 more
openaire   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Exploring the Intersection of Blood Transfusion and Same-Day Computed Tomography Imaging: An Overview of Clinical Risks and Practices

Diagnostics
The use of transfusions, whether involving whole blood or specific blood components, is essential for managing various clinical conditions. Many cases are acute, often requiring post-transfusion imaging evaluation.
Lavinia Alice Bălăceanu, Cristiana Grigore, Cristian-Dorin Gurău, Carmen Giuglea, Gelu-Adrian Popa, Mara Mădălina Mihai, Ion Dina, Beatrice Bălăceanu-Gurău   +7 more
doaj   +1 more source

Grading of Gliomas by Contrast-Enhanced CT Radiomics Features [PDF]

Journal of Biomedical Physics and Engineering
Background: Gliomas, as Central Nervous System (CNS) tumors, are greatly common with 80% of malignancy. Treatment methods for gliomas, such as surgery, radiation therapy, and chemotherapy depend on the grade, size, location, and the patient’s age ...
Mohammad Maskani, Samaneh Abbasi, Hamidreza Etemad-Rezaee, Hamid Abdolahi, Amir Zamanpour, Alireza Montazerabadi   +5 more
doaj   +1 more source

Multi-organ segmentation of abdominal structures from non-contrast and contrast enhanced CT images

Scientific Reports, 2022
Manually delineating upper abdominal organs at risk (OARs) is a time-consuming task. To develop a deep-learning-based tool for accurate and robust auto-segmentation of these OARs, forty pancreatic cancer patients with contrast-enhanced breath-hold ...
Cenji Yu, Chidinma P. Anakwenze, Yao Zhao, Rachael M. Martin, Ethan B. Ludmir, Joshua S.Niedzielski, Asad Qureshi, Prajnan Das, Emma B. Holliday, Ann C. Raldow, Callistus M. Nguyen, Raymond P. Mumme, Tucker J. Netherton, Dong Joo Rhee, Skylar S. Gay, Jinzhong Yang, Laurence E. Court, Carlos E. Cardenas   +17 more
doaj   +1 more source