Results 81 to 90 of about 935,562 (336)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comparative analysis of dynamic contrast-enhanced MRI, dynamic contrast-enhanced CT, and their combination for adrenal tumor diagnosis in men [PDF]

Journal of Men's Health
This study aimed to compare the diagnostic efficacy of dynamic contrast-enhanced computed tomography (CT), dynamic contrast-enhanced Magnetic Resonance Imaging (MRI) and their combination in diagnosing adrenal tumors.
Minghui Yan, Yanan Wang, Lianghong Jiao
doaj   +1 more source

Bleeding Meckel's diverticulum diagnosis: an unusual indication for computed tomography [PDF]

, 2018
Despite the wide use of modern investigation techniques, the diagnosis of complications related to Meckel's diverticulum (MD) remains difficult. Arteriography is commonly indicated for acute bleeding, and radionuclide scans may help in identifying the ...
Danzer, D., Gervaz, P., Platon, A., Poletti, P.-A   +3 more
core  

An automatic deep learning approach for coronary artery calcium segmentation

, 2017
Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed tomography (CT)
Chiappino, D., Della Latta, D., Gori, A., Landini, L., Martini, N., Ripoli, A., Santini, G., Susini, C. L., Valvano, G.   +8 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Contrast enhancement by multi-scale adaptive histogram equalization [PDF]

, 2001
An approach for contrast enhancement utilizing multi-scale analysis is introduced. Sub-band coefficients were modified by the method of adaptive histogram equalization.
Fayad, Laura, Jin, Yinpeng, Laine, Andrew F.   +2 more
core   +2 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Variability of HCC Tumor Diameter and Density Measurements on Dynamic Contrast-Enhanced Computed Tomography

Tomography
Purpose: In cancers imaged using contrast-enhanced protocols, such as hepatocellular carcinoma (HCC), formal guidelines rely on measurements of lesion size (in mm) and radiographic density (in Hounsfield units [HU]) to evaluate response to treatment ...
Siddharth Guha, Abdalla Ibrahim, Pengfei Geng, Qian Wu, Yen Chou, Oguz Akin, Lawrence H. Schwartz, Chuan-Miao Xie, Binsheng Zhao   +8 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Carcinoid tumor of the anterior mediastinum in a 38-year-old woman

Radiology Case Reports, 2020
Mediastinal neuroendocrine tumors (NETs) are very rare. They have been estimated to account for approximately 2%-4% of all anterior mediastinal neoplasms. Carcinoid tumors are a type of NET that can occur in a number of locations.
Khoren Abelian, ME, Omobolaji Ismail Akano, Diana Penha, MD, Erique Guedes-Pinto, MD, Marousa Ntouskou   +4 more
doaj   +1 more source