Results 251 to 260 of about 448,489 (363)

Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review

open access: yesObesity Reviews, Volume 26, Issue 11, November 2025.
ABSTRACT Background Histidine‐containing dipeptides (HCDs) have been reported to have anti‐inflammatory and antidiabetic properties. Yet, no previous reviews have examined the impact of HCDs on Type 2 diabetes (T2D) risk factors (e.g., obesity) and progression (e.g., microvascular and macrovascular complications).
Saeede Saadati   +10 more
wiley   +1 more source

Cdk5 Contributes to Diabetic Islet β Cell and Kidney Injury by Impairing Autophagy

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Over‐activation of cyclin‐dependent kinase 5 (Cdk5) is involved in the development of diabetes and its complications. Mechanistically, Cdk5 expression was upregulated in diabetic mice, which induced attenuated autophagy and increased apoptosis of islet β cells, as well as decreased insulin secretion.
Yuejia Tao   +8 more
wiley   +1 more source

The Na+/K+‐ATPase β1 Subunit is a Kidney ADP‐Ribosyl Cyclase

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
This study highlights that the β1 subunit of Na, K‐ATPase, known as Atp1b1, functions as an ADP‐ribosyl cyclase in rat kidney (kARC). We found that reducing Atp1b1 expression in mouse mesangial cells suppressed angiotensin II (AngII)–induced synthesis of cyclic ADP‐ribose (cADPR) and the associated sustained Ca2+ signaling.
Tae‐Sik Nam   +2 more
wiley   +1 more source

Efficacy of statin pretreatment for the prevention of contrast-induced nephropathy: a meta-analysis of randomised controlled trials

open access: gold, 2011
Liwu Zhang   +7 more
openalex   +1 more source

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