Results 261 to 270 of about 448,489 (363)

Engineered RGD‐Treg‐Exos Targeted Delivery of miR‐218‐5p to Activate Mitophagy and Attenuate Podocyte Injury in Diabetic Kidney Disease

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Tregs‐Exos deliver miR‐218‐5p to increase mitophagy in podocytes by inhibiting the TNC/TLR4/SRC/FUNDC1 pathway. RGD‐Treg‐Exos, engineered to express RGD peptides on the membrane surface, bind to integrins on the surface of podocytes and effectively target podocytes for the delivery of miR‐218‐5p, which increases mitophagy and reduces apoptosis in ...
Zhaochen Guo, Shaohui Gao, Ziyue Wang, Zige Chen, Jinglei Chen, Aiping Duan, Feng Xu, Qinger Wang, Weisong Qin, Caihong Zeng, Zhihong Liu, Hao Bao   +11 more
wiley   +1 more source

RETRACTION: Berberine Alleviates Contrast-Induced Nephropathy by Activating Akt/Foxo3a/Nrf2 Signalling Pathway. [PDF]

J Cell Mol Med
europepmc   +1 more source

Prevalence, risk factors, and short-term outcome of contrast-induced nephropathy among patients with chronic kidney disease: A cross-sectional study from Sri Lanka. [PDF]

Medicine (Baltimore)
Herath N, Rajakrishna P, Suriyaarachi L, Premathilaka S, Perera N, Samarasinghe S, De Silva S, Weerakoon K.   +7 more
europepmc   +1 more source

Prospective Study of the Incidence of Contrast‐induced Nephropathy Among Patients Evaluated for Pulmonary Embolism by Contrast‐enhanced Computed Tomography [PDF]

, 2012
Alice M. Mitchell, Alan E. Jones, James A. Tumlin, Jeffrey A. Kline   +3 more
openalex   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, Volume 12, Issue 39, October 20, 2025.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Development and validation of an AMR-based predictive model for post-PCI contrast-induced nephropathy in patients with acute ST-segment elevation myocardial infarction. [PDF]

Front Cardiovasc Med
Wang Z, Yang S, Li C, Zhou C, Wang C, Jiang T, Chen C, Shao M, Xu T.   +8 more
europepmc   +1 more source

Sodium chloride vs. sodium bicarbonate for the prevention of contrast medium-induced nephropathy: a randomized controlled trial [PDF]

, 2012
Theresia Klima, Andreas Christ, Ivana Marana, Stefan Kalbermatter, Heiko Uthoff, E. Burri, S. Hartwiger, Christian Schindler, Tobias Breidthardt, Giancarlo Marenzi, Christian Mueller   +10 more
openalex   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, Volume 12, Issue 38, October 13, 2025.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

Combination of atorvastatin plus N-acetylcysteine versus atorvastatin alone to prevent contrast-induced nephropathy. [PDF]

Arch Med Sci Atheroscler Dis
Habib M.
europepmc   +1 more source

Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic Encephalopathy

Advanced Science, Volume 12, Issue 37, October 6, 2025.
This study identifies a microRNA (miR)‐216a‐5p/death‐associated protein kinase 1 (DAPK1)/hepatocyte nuclear factor 1 homeobox A (HNF1A)/Netrin‐1 signaling axis in diabetic encephalopathy (DE). In leptin receptor‐deficient (db/db) and streptozotocin (STZ)‐induced diabetic mice, reduced miR‐216a‐5p increases DAPK1 expression, disrupting HNF1A binding to ...
Yang Zhou, Jia‐Xin Kou, Kai Zheng, Zi‐Xuan Guo, Hong‐Wei Fan, Wen‐Lian Li, Lu‐Lu Chu, Jing‐Wen Yin, Li‐Jie Liu, Nadezhda Brazhe, Zhi‐Gao Xiang, Feng Hu, Kai Shu, Ling‐Qiang Zhu, Dan Liu   +14 more
wiley   +1 more source