Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Contrast agents are extensively used to enhance the quality of images in computed tomography (CT) scans for brain exams, vascular imaging, and full-body imaging.
Tanty Fatikasari +2 more
doaj +1 more source
Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction: A phantom study [PDF]
Background To study dose reduction using iterative reconstruction (IR) for pediatric great vessel stent computed tomography (CT). Methods Five different great vessel stents were separately placed in a gel-containing plastic holder within an ...
Breur, J.M.P.J. (Johannes M.P.J.) +7 more
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Detection of ultra-high resonance contrast in vapor cell atomic clocks
We propose and demonstrate a novel detection scheme of clock signals and obtain an ultra-high resonance contrast above 90%. The precision of the signal's detection and the signal-to-noise ratio (SNR) of atomic clock signal is improved remarkably.
Allan +18 more
core +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Feasibility and clinical value of deep learning reconstruction in accelerated MRI of shoulder
Objective To investigate the feasibility and clinical value of the deep learning reconstruction (DLR) algorithm in enhancing image quality and reducing scan time in shoulder MRI.
WANG Xuan*, WANG Hao, WAN Yuntian, CHEN Youfang, NIE Chunyan, DU Yusheng, HE Jian
doaj +1 more source
Aging properties of an anomalously diffusing particle
We report new results about the two-time dynamics of an anomalously diffusing classical particle, as described by the generalized Langevin equation with a frequency-dependent noise and the associated friction. The noise is defined by its spectral density
Aslangul +11 more
core +2 more sources
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
GPI PSF subtraction with TLOCI: the next evolution in exoplanet/disk high-contrast imaging
To directly image exoplanets and faint circumstellar disks, the noisy stellar halo must be suppressed to a high level. To achieve this feat, the angular differential imaging observing technique and the least-squares Locally Optimized Combination of ...
Correia, Carlos +6 more
core +1 more source

