Results 171 to 180 of about 15,851,959 (333)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Contrasting coroners [PDF]

Canadian Medical Association Journal, 2012
Andrew L, McCallum, Albert E, Lauwers, Daniel E, Cass, Michael, Blain   +3 more
openaire   +2 more sources

A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation.

Journal of the American College of Cardiology, 2004
R. Mehran, E. Aymong, E. Nikolsky, Zoran Lasić, I. Iakovou, M. Fahy, G. Mintz, A. Lansky, J. Moses, G. Stone, M. Leon, G. Dangas   +11 more
semanticscholar   +1 more source

Contrast-associated acute kidney injury.

BJA Education, 2020
M. Everson, Kittiya Sukcharoen, Q. Milner   +2 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function.

Circulation, 1999
R. Kim, David S. Fieno, T. Parrish, Kathleen E. Harris, Enn‐ling Chen, Orlando P. Simonetti, J. Bundy, J. Finn, F. Klocke, R. Judd   +9 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Recent Developments and Future Perspectives in Magnetic Resonance Imaging and Computed Tomography Contrast Media. [PDF]

Invest Radiol
Frenzel T, Wels T, Pietsch H, Schöckel L, Seidensticker P, Endrikat J.   +5 more
europepmc   +1 more source

Modeling the acquisition of covert contrast [PDF]

, 2011
Kirby, James
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source