Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Native T1-mapping using cardiovascular magnetic resonance detects myocardium at risk during the first week following myocardial infarction in a swine model and in patients - comparison to contrast-enhanced cine steady-state free precession. [PDF]
BMC Cardiovasc DisordLav T +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Alpha-band echoes evoked by contrast and luminance changes emerge in and travel out from early visual cortex. [PDF]
J VisMorrow A +4 more
europepmc +1 more source
Clinical comparison of transfemoral vs. distal transradial access for lower extremity arteriography. [PDF]
Front SurgFeng Z, Zeng Q, Zhu Y, Wang TY.
europepmc +1 more source
Differential effects of attention and contrast on transition appearance during binocular rivalry. [PDF]
J VisYilmaz C +6 more
europepmc +1 more source
Posterior hypopharyngeal perforation following two-level anterior cervical discectomy and fusion: illustrative case. [PDF]
J Neurosurg Case LessonsSumbizi C +9 more
europepmc +1 more source