Results 1 to 10 of about 866,631 (263)

Discovery of novel 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives as multifunctional MAO-B inhibitors for the treatment of Parkinson’s disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
To discover novel multifunctional agents for the treatment of Parkinson’s disease, a series of 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives was designed, synthesized and evaluated.
Zhongcheng Cao, Xingyue Wang, Tianlong Zhang, Xianwu Fu, Fan Zhang, Jiang Zhu   +5 more
doaj   +1 more source

The Use of Ultrasound Contrast in Interventional Radiology

The Arab Journal of Interventional Radiology, 2023
Ultrasound contrast agents have gained increasing popularity due to the high level of safety, real-time improved visualization, and ability to detect vascularity.
Priyan Tantrige, Khalid Ballal, Michael Kelly, Konstantinos Stefanidis, Dean Huang, Paul S. Sidhu, Gibran Timothy Yusuf   +6 more
doaj   +1 more source

Nanosized T₁ MRI Contrast Agent Based on a Polyamidoamine as Multidentate Gd Ligand

Molecules, 2021
A linear polyamidoamine (PAA) named BAC-EDDS, containing metal chelating repeat units composed of two tert-amines and four carboxylic groups, has been prepared by the aza-Michael polyaddition of ethylendiaminodisuccinic (EDDS) with 2,2-bis(acrylamido ...
Paolo Arosio, Davide Cicolari, Amedea Manfredi, Francesco Orsini, Alessandro Lascialfari, Elisabetta Ranucci, Paolo Ferruti, Daniela Maggioni   +7 more
doaj   +1 more source

Development of liposomal contrast agent with high iodine concentration and minimal effect on renal function

Biochemistry and Biophysics Reports, 2023
Purpose: The use of contrast media is essential to achieve high accuracy in diagnostic imaging. Iodine contrast media, one of these contrast media, has nephrotoxicity as a side effect.
Tomoko Ochi, Hideyuki Nishiofuku, Tomoko Kure, Natsuhiko Saito, Ryosuke Taiji, Nagaaki Marugami, Toshihiro Tanaka, Hiromi Sakai   +7 more
doaj   +1 more source

Agent-Based Image Contrast Enhancement Algorithm

IEEE Access, 2023
One crucial step in several image processing and computer vision applications is Image Contrast Enhancement (ICE), whose main objective is to improve the quality of the information contained in the processed images.
Alberto Luque-Chang, Erik Cuevas, Angel Chavarin, Marco Perez   +3 more
doaj   +1 more source

Pyclen-based Gd complex with ionisable side-chain as a contrastophore for the design of hypersensitive MRI nanoprobes: Synthesis and relaxation studies

Results in Chemistry, 2021
A straightforward method for synthesizing at the multigram scale a low molecular weight PCTA-based gadolinium complex bearing an ionizable oxyacetic chain on the pyridine unit was described, together with its encapsulation within a nanohydrogel matrix ...
Fabienne Dioury, Maité Callewaert, Cyril Cadiou, Céline Henoumont, Michael Molinari, Sophie Laurent, Christophe Portefaix, Marc Port, Francoise Chuburu   +8 more
doaj   +1 more source

Artifact reduction in contrast-enhanced mammography

Insights into Imaging, 2022
Objective To evaluate the effectiveness of a new algorithm developed to reduce artifacts in dual-energy subtraction (DES) contrast-enhanced mammography (CEM) images while preserving contrast enhancement of possible lesions.
Gisella Gennaro, Enrica Baldan, Elisabetta Bezzon, Francesca Caumo   +3 more
doaj   +1 more source

A Photocleavable Contrast Agent for Light-Responsive MRI

Pharmaceuticals, 2020
Thanks to its innocuousness and high spatiotemporal resolution, light is used in several established and emerging applications in biomedicine. Among them is the modulation of magnetic resonance imaging (MRI) contrast agents’ relaxivity with the aim to ...
Friederike Reeßing, Sèvrin E. M. Huijsse, Rudi A. J. O. Dierckx, Ben L. Feringa, Ronald J.H. Borra, Wiktor Szymański   +5 more
doaj   +1 more source

Intraperitoneal administration for sustained photoacoustic contrast agent imaging

Photoacoustics, 2022
Photoacoustic (PA) imaging at 1064 nm in the second near-infrared (NIR-II) has attracted recent attention. We recently reported a surfactant-based formulation of a NIR-II dye (BIBDAH) for NIR-II PA contrast.
Hailey I. Kilian, Chenshuo Ma, Huijuan Zhang, Maomao Chen, Anoop Nilam, Breandan Quinn, Yuqi Tang, Jun Xia, Junjie Yao, Jonathan F. Lovell   +9 more
doaj   +1 more source

Use of Manganese Supplement as an Alternative to Oral Contrast Agents for Gastrointestinal Tract Magnetic Resonance Imaging [PDF]

Iranian Journal of Medical Physics
Introduction: This research aims to find an alternative oral contrast agents that can be used in magnetic resonance imaging (MRI) of the gastrointestinal (GI) tract, this contrast agent must be with no or minimum side effects and gives a best imaging ...
zainab mankhi, Khalid Riah, Ahmed Abdul-Lettif   +2 more
doaj   +1 more source