Results 161 to 170 of about 899,795 (311)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Design of Novel Protein-based MRI Contrast Agernets with High Relaxivity and Stability for Biomedical Imaging

Magnetic resonance imaging (MRI) is the leading imaging technique for disease diagnostics. MRI contrast agents facilitate MRI technique to obtain tissue-specific image with improved sensitivity and signal-to-noise ratio.
Xue, Shenghui
core   +1 more source

Ultra-low-dose left ventricular injection-guided computed tomographic angiography prior to transcatheter aortic valve implantation: A novel technique for imaging

Türk Kardiyoloji Derneği Arşivi, 2019
Beytullah Çakal, Sinem Deniz Çakal, Aydın Yıldırım   +2 more
doaj   +1 more source

Automated scout-image-based estimation of contrast agent dosing: a deep learning approach. [PDF]

BMC Med Imaging
Schirrmeister RT, Taleb L, Friemel P, Reisert M, Bamberg F, Weiß J, Rau A.   +6 more
europepmc   +1 more source

Contrast Agent [PDF]

, 2020
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Human Transthyretin with a Tailored Gd(III) Complex as a High-Relaxivity MRI Contrast Agent. [PDF]

Inorg Chem
Bindi J, Kubrak A, Lei Y, Kaster M, Cerofolini L, Ravera E, Meade TJ, Fragai M, Parigi G.   +8 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Agent–Based Keynesian Macroeconomics - An Evolutionary Model Embedded in an Agent–Based Computer Simulation

Subject of the present study is the agent-based computer simulation of Agent Island. Agent Island is a macroeconomic model, which belongs to the field of monetary theory.
Oeffner, Marc
core  

Biodegradable Iodinated Polymeric Nanoparticle as a Computed Tomography Contrast Agent for Direct Imaging of Cerebral Thrombus. [PDF]

ACS Nano
Park HJ, Park S, Chung IJ, Jang HJ, Lee L, Kim TH, Kim DE, Ahn CH.   +7 more
europepmc   +1 more source