Results 141 to 150 of about 1,575,773 (328)
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
A NON-LINEAR TECHNIQUE FOR THE ENHANCEMENT OF EXTREMELY NON-UNIFORM LIGHTING IMAGES
Havacılık ve Uzay Teknolojileri Dergisi, 2007 At night scenes and under nonuniform lighting conditions, either the low intensity areas or the high intensity areas cannot be clearly seen. Various image processing techniques have been developed to recover the meaningful
Osman Nuri Uçan , Ender Öğüşlü
doaj
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
MR Image Contrast Enhancement by Wavelet-based Contourlet Transform [PDF]
International Journal Bioautomation, 2016 The contrast of magnetic resonance (MR) image local regions is low, edges blurred and image contains noise. To improve image contrast of local regions and solve the problem of noise enlarging, an MR image contrast enhancement algorithm by wavelet-based ...
Zhongliang Luo, Yingbiao Jia
doaj
Microchannel spatial light modulator [PDF]
The Microchannel Spatial Light Modulator (MSLM), a versatile, highly sensitive, and optically addressed device being developed for real time optical information processing is discussed. The MSLM operates by converting an input optical image into a charge
Warde, C.
core +1 more source
Enhancement of BOLD-contrast sensitivity by single-shot multi-echo functional MR imaging [PDF]
, 1999 Stefan Posse +9 more
openalex +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Enhanced tumor detection in the presence of liver cirrhosis: Experimental study on the diagnostic value of a superparamagnetic iron oxide MR imaging contrast agent (NSR 0430) [PDF]
, 1999 Rainald Bachmann +5 more
openalex +1 more source