Results 141 to 150 of about 3,372,624 (300)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Derivation of Optimal Global Equalization Function with Variable Size Block Based Local Contrast Enhancement

Journal of Measurement Science and Instrumentation, 2010
A conventional global contrast enhancement is difficult to apply in various images because image quality and contrast enhancement are dependent on image characteristics largely.And a local contrast enhancement not only causes a washed-out effect,but also
Ralph Oyini Mbouna, Young-joon HAN
doaj  

Research of adaptive local contrast enhancement

, 2010
碩士近年來數位影像處理已有不少應用在安全監控系統中，而清楚 且明暗適中的影像，已經是數位影像的基本需求,但由於攝影環境的 場景複雜，常常會增加影像資訊處理的困難，或者讓處理過後的影 像只有特定部分得到補正而造成功能上的限制，無法符合一般使用 者的需求。 經由模擬的結果顯示出這新式響應曲線與人眼對光的響應曲線 非常相似，都是一個對數型態的轉換函數。這樣的曲線非常適合用 來當作數位影像輸出。除了在影像品質上面做改善，另外在運算處 理速度上也需達到即時的要求，本模擬運算皆由時域轉為頻域運 算 ...
湯克中; Tang, Ke-chung
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Numeric Analysis of Polarized Lidar Contrast Enhancement Across Diverse Targets in Fog. [PDF]

Sensors (Basel)
Petzi M, Reitzle D, Kienle A.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Fabry-Pérot Microscopy for Improved Contrast Enhancement and Quantitative Phase Imaging. [PDF]

J Biophotonics
Pittrich J, von Köller G, Dillitzer C, Sandner D, Emken E, Sistermanns J, Wolf Z, Schlegel M, Weirich G, Kienberger R, Hayden O, Iglev H.   +11 more
europepmc   +1 more source

Riparian and stream enhancement project evaluation

, 2002
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Oct. 19, 2006)"8-30-02."

core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source