Results 191 to 200 of about 82,618 (247)

Single‐Chain Anti‐IL‐1β Antibody Carried by Outer Membrane Vesicles of Bacteroides fragilis Alleviates Tubular Inflammation in Chronic Kidney Disease

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Engineered Bacteroides fragilis outer membrane vesicles carrying anti‐IL‐1β scFv and kidney‐targeting peptides alleviate renal inflammation and injury in CKD mouse models via precise delivery and NF‐κB inhibition. ABSTRACT Microinflammation is a key driver of chronic kidney disease (CKD) progression, with interleukin‐1β (IL‐1β) playing a pivotal role ...
Liang Li   +6 more
wiley   +1 more source

Catheter Ablation and Device Therapy in Patients With Transthyretin Amyloid Cardiomyopathy: A Review of Non‐Pharmacological Therapy

open access: yesJournal of Arrhythmia, Volume 42, Issue 1, February 2026.
Transthyretin cardiomyopathy (ATTR‐CM) frequently coexists with atrial fibrillation, atrial flutter, and atrial tachycardia as well as occasionally ventricular arrhythmias and often conduction abnormalities, necessitating management for arrhythmias. Therefore, for arrhythmia specialists, the ability to diagnose ATTR‐CM and proficiency in arrhythmia ...
Hisanori Kanazawa   +12 more
wiley   +1 more source

GLIS2 Promotes Epithelial‐Mesenchymal Transition and Gastric Cancer Progression by Regulating BGN to Activate the Wnt/β‐Catenin Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 2, February 2026.
ABSTRACT This study elucidates the mechanism by which GLIS Family Zinc Finger 2 (GLIS2) promotes epithelial‐mesenchymal transition (EMT) in gastric cancer through biglycan (BGN) activation and Wnt/β‐catenin stimulation. By analyzing 18 pairs of GC tissues and establishing in vitro models (combining GLIS2 knockdown/BGN overexpression with Wnt pathway ...
Juan Yan, Ya‐Peng Deng
wiley   +1 more source

Nicorandil in preventing contrast-induced nephropathy in patients undergoing cardiac catheterization procedures: a systematic review and meta-analysis. [PDF]

open access: yesAnn Med Surg (Lond)
Waseem R   +14 more
europepmc   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

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