Results 211 to 220 of about 82,677 (285)

The Na+/K+‐ATPase β1 Subunit is a Kidney ADP‐Ribosyl Cyclase

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
This study highlights that the β1 subunit of Na, K‐ATPase, known as Atp1b1, functions as an ADP‐ribosyl cyclase in rat kidney (kARC). We found that reducing Atp1b1 expression in mouse mesangial cells suppressed angiotensin II (AngII)–induced synthesis of cyclic ADP‐ribose (cADPR) and the associated sustained Ca2+ signaling.
Tae‐Sik Nam   +2 more
wiley   +1 more source

Engineered RGD‐Treg‐Exos Targeted Delivery of miR‐218‐5p to Activate Mitophagy and Attenuate Podocyte Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Tregs‐Exos deliver miR‐218‐5p to increase mitophagy in podocytes by inhibiting the TNC/TLR4/SRC/FUNDC1 pathway. RGD‐Treg‐Exos, engineered to express RGD peptides on the membrane surface, bind to integrins on the surface of podocytes and effectively target podocytes for the delivery of miR‐218‐5p, which increases mitophagy and reduces apoptosis in ...
Zhaochen Guo   +11 more
wiley   +1 more source

Prevention of contrast induced nephropathy; a cardiology point of view [PDF]

open access: yesJournal of Nephropharmacology, 2015
Hashemi Mohammad   +2 more
doaj  

Does N-Acetylcysteine Reduce the Incidence of Contrast-Induced Nephropathy and Clinical Events in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction?

open access: hybrid, 2011
Akihito Tanaka   +7 more
openalex   +2 more sources

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang   +11 more
wiley   +1 more source

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