Results 21 to 30 of about 8,467,443 (412)

Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug–Drug Interactions in Rats

Pharmaceutics, 2023
Gadoxetate, a magnetic resonance imaging (MRI) contrast agent, is a substrate of organic-anion-transporting polypeptide 1B1 and multidrug resistance-associated protein 2.
Nicola Melillo, Daniel Scotcher, J. Gerry Kenna, Claudia Green, Catherine D. G. Hines, Iina Laitinen, Paul D. Hockings, Kayode Ogungbenro, Ebony R. Gunwhy, Steven Sourbron, John C. Waterton, Gunnar Schuetz, Aleksandra Galetin   +12 more
doaj   +1 more source

Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats

Scientific Reports, 2020
Gadolinium based contrast agents (GBCAs) are widely used in clinical MRI since the mid-1980s. Recently, concerns have been raised that trace amounts of Gadolinium (Gd), detected in brains even long time after GBCA application, may cause yet unrecognized ...
Johanna Habermeyer, Janina Boyken, Julia Harrer, Fabio Canneva, Veronika Ratz, Sandra Moceri, Jakob Admard, Nicolas Casadei, Gregor Jost, Tobias Bäuerle, Thomas Frenzel, Christoph Schmitz, Gunnar Schütz, Hubertus Pietsch, Stephan von Hörsten   +14 more
doaj   +1 more source

Korean Clinical Practice Guidelines for Adverse Reactions to Intravenous Iodinate and MRI-Gadolinium Contrast Agents: Revised Clinical Consensus and Recommendations (3rd Edition, 2022)

대한영상의학회지, 2022
The Korean Society of Radiology and Medical Guidelines Committee amended the existing 2016 guidelines to publish the “Korean Clinical Practice Guidelines for Adverse Reactions to Iodide Contrast for Injection and Gadolinium Contrast for MRI: The ...
Se Won Oh, So Young Park, Hwan Seok Yong, Young Hun Choi, Min Jae Cha, Tae Bum Kim, Ji Hyang Lee, Sae Hoon Kim, Jae Hyun Lee, Gyu Young Hur, Jae Yeon Hwang, Sejoong Kim, Hyo Sang Kim, Ji Young Ryu, Miyoung Choi, Chi-Hoon Choi   +15 more
doaj   +1 more source

Hypersensitivity Reactions to Iodinated Contrast Media

Biomedicines, 2022
At present, iodinated contrast media (ICM) are mostly non-ionic, have low osmolality, and are safe. Even if adverse drug reactions (ADRs) occur, most are chemo-toxic symptoms and require only observation or H1 antihistamines. However, rare, unpredictable,
Tsu-Man Chiu, Sung-Yu Chu
doaj   +1 more source

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

Allergy. European Journal of Allergy and Clinical Immunology, 2020
Immediate and nonimmediate hypersensitivity reactions to iodinated contrast media (ICM) have been reported to occur in a frequency of about 0.5%‐3% of patients receiving nonionic ICM.
Marta E. Torres, A. Trautmann, Ingrid B hm, K. Hofmeier, A. Barbaud, S. Bavbek, P. Bonadonna, J. Cernadas, A. Chiriac, F. Gaeta, A. G. Arnau, H. Kang, E. Moreno, K. Brockow   +13 more
semanticscholar   +1 more source

Optimization of Iron Oxide Tracer Synthesis for Magnetic Particle Imaging

Nanomaterials, 2018
The optimization of iron oxide nanoparticles as tracers for magnetic particle imaging (MPI) alongside the development of data acquisition equipment and image reconstruction techniques is crucial for the required improvements in image resolution and ...
Sabina Ziemian, Norbert Löwa, Olaf Kosch, Daniel Bajj, Frank Wiekhorst, Gunnar Schütz   +5 more
doaj   +1 more source

Rôle of contrast media viscosity in altering vessel wall shear stress and relation to the risk of contrast extravasations [PDF]

, 2016
Iodinated contrast media (CM) are the most commonly used injectables in radiology today. A range of different media are commercially available, combining various physical and chemical characteristics (ionic state, osmolality, viscosity) and thus ...
Li, Wenguang, Paul, Manosh C., Roditi, Giles, Sakellariou, Sophia   +3 more
core   +1 more source

Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis [PDF]

, 2011
<p>Background and Purpose: Iodinated contrast is increasingly used in CT perfusion or angiographic examinations in acute stroke. Increased risk of intracranial hemorrhage (ICH) complicating microcatheter contrast injections has recently been ...
Evelyn Teasdale, Ferghal McVerry, Keith W. Muir, Niall J.J. MacDougall, Sally Baird, Tracey Baird, Wilcox J   +6 more
core   +1 more source

Contrast Media: Are There Differences in Nephrotoxicity among Contrast Media? [PDF]

BioMed Research International, 2014
Iodinated contrast agents are usually classified based upon their osmolality—high, low, and isosmolar. Iodinated contrast agents are also nephrotoxic in some but not all patients resulting in loss of glomerular filtration rate. Over the past 30 years, nephrotoxicity has been linked to osmolality although the precise mechanism underlying such a link has
openaire   +2 more sources

Iodinated contrast media-induced hyperthyroidism

Journal of Medical Science, 2020
Currently, iodinated contrast media (ICM) is widely used in radiology, therefore numerous patients are exposed to contrast administration during diagnostic and interventional procedures. ICM contains an amount of iodine well above the recommended dietary
Katarzyna Pelewicz, Piotr Miśkiewicz
doaj   +1 more source