Results 121 to 130 of about 4,213,516 (338)

The Frontiers of Product Liability for Adverse Reactions to the Contrast Medium [PDF]

, 2008
Chang-Seon Lim
openalex   +1 more source

High-pitch CT pulmonary angiography (CTPA) with ultra-low contrast medium volume for the detection of pulmonary embolism: a comparison with standard CTPA [PDF]

, 2023
Tobias Schönfeld, Patrick Seitz, Christian Krieghoff, Slavica Ponorac, Alexander Wötzel, Stefan Olthoff, Sebastian Schaudt, Jonas Steglich, Matthias Gutberlet, Robin F. Gohmann   +9 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Magna Graecia transcatheter aortic valve implantation registry: data on contrast medium osmolality and postprocedural acute kidney injury

, 2021
Fortunato Iacovelli, Antonio Pignatelli, Alessandro Cafaro, Eugenio Stabile, Luigi Salemme, Angelo Cioppa, Armando Pucciarelli, Francesco Spione, Francesco Loizzi, Emanuela De Cillis, Vincenzo Pestrichella, Alessandro Santo Bortone, Tullio Tesorio, Gaetano Contegiacomo   +13 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

VesselTransGAN to CT Imaging: A Contrast Medium Free CTA Solution

IEEE Access
Computed Tomography Angiography (CTA) is vital for detecting and planning treatment for vascular disease, but its use of contrast medium limits viability for patients with renal insufficiency.
Yun Hua, Suyan Bian, Pan Liu, Shaodong Zhu, Jing Jing, Yan Zhuang, Menglu Li, Xu Chen, Chongyou Rao, Xiaoyu Jin, Kunlun He   +10 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Contrast-associated acute kidney injury, new findings and old believes [PDF]

Journal of Nephropathology, 2019
Mohamad Ali Dayani, Mohammadali Mohajel Shoja, Mohammadreza Ardalan   +2 more
doaj   +1 more source

An Individually Optimized Protocol of Contrast Medium Injection in Enhanced CT Scan for Liver Imaging [PDF]

, 2017
Shi‐Ting Feng, Hongzhang Zhu, Zhenpeng Peng, Li Huang, Zhi Dong, Ling Xu, Kun Huang, Xufeng Yang, Zhi Lin, Zi-Ping Li   +9 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source