Results 281 to 290 of about 4,095,028 (342)

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Excretion of contrast medium

The British Journal of Radiology, 1974
I was most interested to read “The effects of haemodialysis on excretion urography in severe chronic renal failure” (Rees et al., 1974). I believe some observations from our recent experiments may be of interest and possibly help to explain the disappointing effects which haemodialysis may have on improving the study.
J. H. Jones   +4 more
openaire   +6 more sources

Contrast Medium or No Contrast Medium for Prostate Cancer Diagnosis. That Is the Question

Journal of Magnetic Resonance Imaging, 2020
The benefits and drawbacks of the dynamic contrast‐enhanced MRI sequence for prostate cancer diagnosis are increasingly being recognized, with many centers adopting the biparametric (bp) MRI approach as the default initial approach. The abandonment of the routine use of contrast medium requires an assessment of the loss of diagnostic power against the ...
Anwar R. Padhani   +2 more
openaire   +4 more sources

Contrast Medium Use

The American Journal of Cardiology, 2006
Various properties of iodinated contrast media (osmolality, ionic versus nonionic, and viscosity) may contribute to contrast-induced nephropathy (CIN). Therefore, the choice of contrast medium affects the risk for CIN. There is good evidence that low-osmolar contrast media are less nephrotoxic than high-osmolar contrast media in patients at increased ...
Davidson, C   +6 more
openaire   +4 more sources

Angiographic Contrast Mediums

Postgraduate Medicine, 1968
Radiologists who inject radiopaque substances into vessels practice a demanding art. They must consider the type, bore and length of the catheter; know precisely the iodine content, viscosity and toxicity of different contrast mediums; and decide what injection to use and how rapidly to inject.
Paul C. Hodges, Harry W. Fischer
openaire   +3 more sources

The Contrast Medium

1982
During the second world war, barium was the generally accepted contrast medium for examination of the small intestine. The 40-year-old custom of mixing nutrients with the contrast medium was abandoned since this appeared to be the main reason that good mucosal patterns could not be obtained. The importance of fine demonstration of anatomical detail had
Johan L. Sellink, Roscoe E. Miller
openaire   +2 more sources

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