Results 81 to 90 of about 9,155,379 (405)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Hysterosalpingography with Oil-Soluble Contrast Medium Does Not Increase Newborn Hypothyroidism

open access: yesInternational Journal of Endocrinology, 2022
Objective. Hysterosalpingography (HSG) with oil-soluble contrast medium (OSCM) improves pregnancy rates in women with idiopathic infertility. However, OSCM has high iodine content and slow clearance resulting in potential iodine excess.
Divya M. Mathews   +7 more
doaj   +1 more source

Topological phase transition in wire medium enables high Purcell factor at infrared frequencies

open access: yes, 2015
In this paper, we study topological phase transition in a wire medium operating at infrared frequencies. This transition occurs in the reciprocal space between the indefinite (open-surface) regime of the metamaterial to its dielectric (closed-surface ...
Kosulnikov, S. Yu.   +2 more
core   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Feasibility of utilizing ultra-low-dose contrast medium for pancreatic artery depiction using the combination of advanced virtual monoenergetic imaging and high-concentration contrast medium: an intra-patient study

open access: yesInsights into Imaging, 2021
Objectives The least amount of contrast medium (CM) should be used under the premise of adequate diagnosis. The purpose of this study is to evaluate the feasibility of utilizing ultra-low-dose (224 mgI/kg) CM for pancreatic artery depiction using the ...
Juan Li   +9 more
doaj   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

The impact of the medium and the jet-medium coupling on jet measurements at RHIC and LHC [PDF]

open access: yesarXiv, 2015
We compare a perturbative QCD-based jet-energy loss model to the measured data of the pion nuclear modification factor and the high-pT elliptic flow at RHIC and LHC energies. This jet-energy loss model (BBMG) is currently coupled to state-of-the-art hydrodynamic descriptions.
arxiv  

Efficient diffraction control using a tunable active-Raman gain medium [PDF]

open access: yesPhys. Rev. A 107, 023701 (2023)
We present a new scheme to create all-optical tunable and lossless waveguide using a controllable coherent Raman process in an atomic rubidium vapor in N-type configuration. We employ a Gaussian Raman field and a Laguerre-Gaussian control field to imprint a high-contrast tunable waveguide-like feature inside the atomic medium.
arxiv   +1 more source

Quantitating contrast medium-induced nephropathy: controlling the controls.

open access: yesRadiology, 2013
Davenport et al and McDonald et al find no evidence of nephropathy in patients with mild renal failure, even if other common risks to kidney function exist; for patients with more severe renal failure, if we assume that the real chances of contrast ...
J. Newhouse, A. Roychoudhury
semanticscholar   +1 more source

On the missing 2175 Angstroem-bump in the Calzetti extinction curve

open access: yes, 2011
The aim of the paper is to give a physical explanation of the absence of the feature in the Calzetti extinction curve. We analyze the dust attenuation of a homogeneous source seen through a distant inhomogeneous distant screen.
Allain   +33 more
core   +1 more source

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