Results 111 to 120 of about 5,554,949 (261)

The predictive value of the product of contrast medium volume and urinary albumin/creatinine ratio in contrast-induced acute kidney injury

open access: yesRenal Failure, 2017
Preexisting renal impairment and the amount of contrast media are the most important risk factors for contrast-induced acute kidney injury (CI-AKI). We aimed to investigate whether the product of contrast medium volume and urinary albumin/creatinine ...
Chunrui Wang   +7 more
doaj   +1 more source

Contrast enhancement efficacy of iodinated contrast media: Effect of molecular structure on contrast enhancement

open access: yes, 2018
Purpose: To investigate the contrast enhancement in DSA images based on the X-ray absorption characteristics of iodinated contrast media. Methods: We have derived a new formula of predicting the pixel value ratio of two different contrast media and ...
Mitsuru Ikeda   +6 more
core   +1 more source

Spatial Frequency Discrimination of Band-limited Periodic Targets: Effects of Stimulus Contrast, Bandwidth and Retinal Eccentricity [PDF]

open access: yes, 1992
Two experiments were conducted to explore the ability of human observers to discriminate the spatial frequency of briefly-presented, Gaussian-truncated sinewave gratings.
Greenlee, Mark W.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Axiomatization of ratio equilibria in public good economies [PDF]

open access: yes, 2001
Using consistency properties, we characterize the cost-sharing scheme arising from the ratio equilibrium concept for economies with public goods. The characterization turns out to be surprisingly simple and direct.
Wooders, Myrna Holtz   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Computing contrast ratio in images using local content information

open access: yes, 2015
It is well know that a measure of contrast in images is not yet fully defined. The conventional measures of contrast consist of global computations and therefore they have a poor performance.
L. Platisa   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The effects of delay-to-reinforcement, response requirement and schedule duration on performance under fixed-ratio schedules [PDF]

open access: yes, 2011
Experiment 1 examined the effects of delay-to-reinforcement on between-ratio pausing in multiple fixed-ratio 5 fixed-ratio 5 schedules. In one component the reinforcer was delivered immediately on completion of the ratio, and in the other there was a ...
Harris, Aimee Rebecca
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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