Results 221 to 230 of about 3,408,895 (339)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Significant Age-Related Visual Declines but Preserved Binocular Summation of Contrast Sensitivity and Visual Acuity Across Adulthood. [PDF]

Invest Ophthalmol Vis Sci
Peñaloza B, Kwon M.
europepmc   +1 more source

Relation between Pupil Response and Feedback during Contrast Sensitivity Measurement through Tinted Lenses

, 2017
Tim Schilling, Hamed Bahmani, Arne Ohlendorf, Siegfried Wahl   +3 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Lateral inhibition in V1 controls neural and perceptual contrast sensitivity. [PDF]

Nat Neurosci
Del Rosario J, Coletta S, Kim SH, Mobille Z, Peelman K, Williams B, Otsuki AJ, Del Castillo Valerio A, Worden K, Blanpain LT, Lovell L, Choi H, Haider B.   +12 more
europepmc   +1 more source

Spatial and temporal contrast sensitivity of neurones in areas 17 and 18 of the cat's visual cortex.

, 1978
J. Anthony Movshon, Ian D. Thompson, D.J. Tolhurst   +2 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Validation and evaluation of visual acuity and contrast sensitivity with a new digital device: OPTOTAB®. [PDF]

Ophthalmic Physiol Opt
Ponce-García V, Silva-Viguera MC, García-Romera MC, Guerra-Sancho Y, Heredia-Ríos N, Bautista-Llamas MJ.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Optimizing Contrast Sensitivity Perimetry for Clinical Use

Journal of Ophthalmic & Vision Research, 2013
Mitchell W Dul
doaj