Results 251 to 260 of about 1,576,352 (284)

A 14‐Year Study of Serum Glial Fibrillary Acidic Protein and Total Tau in Premanifest Huntington's

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT There is a pressing need for blood biomarkers that can identify Huntington's disease (HD) gene carriers' proximity to manifest disease. We previously examined serial serum neurofilament light (NfL) concentrations in 21 premanifest HD gene carriers and 14 controls over 14 years, finding that NfL demonstrates high prognostic value and distinct ...
Natalia E. Owen, Zanna J. Voysey, Jonathan A. Holbrook, Maura Malpetti, Clara Le Draoulec, Lennart R. B. Spindler, Anna O. G. Goodman, Alpar S. Lazar, Roger A. Barker   +8 more
wiley   +1 more source

Pushing the envelope: the feasibility of using a mailed contrast sensitivity test to prioritise cataract waiting lists. [PDF]

Eye (Lond)
Bianchi E, Reddingius PF, Rathore M, Lindfield D, Crabb DP, Jones PR.   +5 more
europepmc   +1 more source

Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials

Arthritis Care &Research, EarlyView.
Objective Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.
Jemma Hudson, Mari Imamura, Clare Robertson, Daniel Whibley, Lorna Aucott, Katie Gillies, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole K. Y. Tang, Gary J. Macfarlane, Miriam Brazzelli   +11 more
wiley   +1 more source

Featural Representation and Internal Noise Underlie the Eccentricity Effect in Contrast Sensitivity. [PDF]

J Neurosci
Xue S, Fernández A, Carrasco M.
europepmc   +1 more source

Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care Electronic Health Records

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew, George Peat, Emma Parry, Ross Wilkie, Kelvin P. Jordan, Jonathan C. Hill, Dahai Yu   +6 more
wiley   +1 more source

Associations between the cause of amblyopia and pre-treatment contrast sensitivity, stereoacuity, fixation, and nystagmus. [PDF]

Heliyon
Jia Y, Ye Q, Liu J, Feng L, Xu Z, He Y, Zhou Y, Chen X, Yao Y, Thompson B, Li J.   +10 more
europepmc   +1 more source

Juvenile Idiopathic Arthritis, Earnings, and Work Loss: A Nationwide Matched Cohort Study

Arthritis Care &Research, EarlyView.
Objective This study compares trajectories of earnings and work loss in individuals with juvenile idiopathic arthritis (JIA) versus matched comparators from the general population. Methods Patients with JIA (n = 4,737) were identified in the Swedish National Patient Register (2001–2017) and individually matched to up to five general population ...
Heather Miller, Martin Neovius, Erik Sundberg, Johan Askling, Gustaf Bruze   +4 more
wiley   +1 more source

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar, Jocelyn L Bowden, Kim L Bennell, Andrew M Briggs, Stephen J Bunker, Rana S Hinman, Thorlene Egerton, Simon D French, Marie Pirotta, Karen Schuck, Venkatesha Venkatesha, Nicholas A Zwar, David J Hunter   +12 more
wiley   +1 more source

Reduced contrast sensitivity function is correlated with changes to cone photoreceptors in simple high myopia. [PDF]

Front Neurosci
Wang J, Liu X, Huang J, Deng R, Zhao S, Chen Y, Chen Z, Wang Y, Rong Y, Liu Q, Qu J, Mao X.   +11 more
europepmc   +1 more source

Degradation of Photopic and Mesopic Contrast Sensitivity Function in High Myopes With Partial Posterior Vitreous Detachment. [PDF]

Transl Vis Sci Technol
Zhao J, Xiao M, Zhu Y, Gong Q, Qu J, Lu F, Hu L.   +6 more
europepmc   +1 more source