Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The Next Generation: Aspects of Grammatical Variation in the Speech of some London Preadolescents
, 2007 PhDThis thesis is a sociolinguistic investigation into aspects of non-phonological variation in a group of preadolescents recorded in outer east London.
Levey, Stephen
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Error evaluation of partial scattering functions obtained from contrast-variation small-angle neutron scattering. [PDF]
J Appl CrystallogrMayumi K +4 more
europepmc +1 more source
Contrast Variation Small Angle Neutron Scattering Investigation of Micro- and Nano-Sized TATB. [PDF]
Materials (Basel), 2019 Song P +8 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
International audienceSmall-angle X-ray scattering (SAXS) has evolved over the past decades into an essential structural biology technique for the study of conformational states of solubilized biomacromolecules and assemblies.
Franzetti, Bruno +7 more
core +1 more source
Enhanced estimation method for partial scattering functions in contrast variation small-angle neutron scattering via Gaussian process regression with prior knowledge of smoothness. [PDF]
J Appl CrystallogrObayashi I +3 more
europepmc +1 more source
Diffusion Decoupling in Binary Colloidal Systems Observed with Contrast Variation Multispeckle Diffusing Wave Spectroscopy. [PDF]
Langmuir, 2019 Higler R, Frijns RAM, Sprakel J.
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Wavefront Amplitude Variation of TPF's High Contrast Imaging Testbed: Modeling and Experiment
, 2005 Knowledge of wavefront amplitude is as important as the knowledge of phase for a coronagraphic high contrast imaging system. Efforts have been made to understand various contributions of the amplitude variation in Terrestrial Planet Finder's (TPF) High ...
Moody, Dwight C. +4 more
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