Results 141 to 150 of about 133,406 (328)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Contrastive Analysis of Russian-Polish Consonantism

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2012
The article deals with the aspects to present phonetic and phonological systems of The Russian and Polish languages. At the same time similarities and differences in the two languages compared reveal both universal and unique, specific characteristics in
O V Lazareva, E O Morgunova
doaj  

Contrastive analysis of proverbs

open access: yesRadovi. Razdio filoloških znanosti, 2018
Poslovice su i bile i jesu važno jezično sredstvo, te prema tome bi i učenik stranog jezika morao raspolagati jednim fondom poslovica, i to, radi nijansiranja i proširivanja jezične kompetencije i radi poboljšanja prevodilačke sposobnosti. Kontrastiranje poslovica poboljšuje nastavu stranog jezika.
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Statistical parameters and analysis of local contrast gloss

open access: gold, 2008
Antti Oksman   +2 more
openalex   +1 more source

Comparative Genomic Analysis of Rice with Contrasting Photosynthesis and Grain Production under Salt Stress [PDF]

open access: gold, 2019
Chakkree Lekklar   +6 more
openalex   +1 more source

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