Results 61 to 70 of about 6,056,553 (315)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Old-Age Pension Insurance in ZUS and KRUS in the Context of the Insured and Public Finances
Studia Ekonomiczne i Regionalne, 2019 Subject and purpose of work: The subject of this paper was to assess the old-age pension insurance in ZUS (Social Insurance Institution) and KRUS (Agricultural Social Insurance Fund) from the perspective of a person insured and the public finances.
Podstawka Łukasz
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Four Santa Elena monuments from Balancan museum, Tabasco, Mexico
RUDN Journal of World HistoryThe relevance of the research topic is due to the fact that the corpus of hieroglyphic inscriptions of Santa Elena, located in the municipality of Balancan in the territory of the modern state of Tabasco, is not large, and most of the references to its ...
Sergei V. Vepretskii +3 more
doaj +1 more source
Journal of Computational and Graphical Statistics, 2012 In order to interpret the biplot it is necessary to know which points – usually variables – are the ones that are important contributors to the solution, and this information is available separately as part of the biplot’s numerical results. We propose a new scaling of the display, called the contribution biplot, which incorporates this diagnostic ...
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
SED-EEW-SeisComP-contributions
<h2>What's Changed</h2> <ul> <li>Add L2Norm::reset method in envelope library necessary for SC API 16 by @gempa-jabe in https://github.com/SED-EEW/SED-EEW-SeisComP-contributions/pull/39</li> <li>Fix envelope latency ...
Fred Massin +17 more
core +1 more source
Сибирское юридическое обозрение, 2018 The article analyzes the change in the social insurance system for self-employed Brazilian citizens, thanks to two programs introduced in the 2000s, which showed a high result in terms of legalization and inclusion in the social security system of such ...
A. V. Burlak
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
From margins to mainstream: decolonizing science and promoting diversity for the future of STEM
Frontiers in EducationDecolonizing science is essential for dismantling entrenched biases that privilege Western methodologies and marginalize valuable contributions from non-dominant regions.
Roksana Khalid, Isaiah J. Ting
doaj +1 more source