Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Malaria elimination practices in China from the perspective of health system and social development. [PDF]
Infect Dis PovertySong X +8 more
europepmc +1 more source
Enhancing Efficiency in Coal-Fired Boilers Using a New Predictive Control Method for Key Parameters. [PDF]
Sensors (Basel)Li Q +10 more
europepmc +1 more source
Optimized super-twisting active disturbance rejection control based on nonlinear extended state observer for aircraft attitude stabilization. [PDF]
Sci RepYazdiniya F, Ansarifar G.
europepmc +1 more source
Do Children and Parents Agree on the Level of Asthma Control? A Systematic Review. [PDF]
Pediatr PulmonolBousema S +5 more
europepmc +1 more source
The Effects of a Health Literacy Promotion Program on Health Behaviors and Blood Pressure Levels Among Uncontrolled Hypertensive Patients: A Quasi-Experimental Study. [PDF]
J Prim Care Community HealthTesamut L, Sungwan P, Somrit J.
europepmc +1 more source
An adaptive model predictive control approach for robust load frequency control under renewable energy disturbances. [PDF]
Sci RepAyman M, Attia MA, Asim AM.
europepmc +1 more source