Results 111 to 120 of about 6,764,216 (308)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Optimizing Motor Coordination in Children with Developmental Coordination Disorder: Mini-Handball vs. Motor Skills Training

Sports
Children with Developmental Coordination Disorder (DCD) experience motor competence challenges that hinder their participation in physical activities and affect daily functioning.
Hurshida Bekmanova, Orifjon Saidmamatov, Jasurbek Jammatov, Taxirbek Salayev, Raximov Quvondiq, Shikhov Gayrat, Olga Vasconcelos, Rita Barros, Claúdia Sousa, Paula Rodrigues   +9 more
doaj   +1 more source

Evaluation The Activities of Health Control Staff and Laboratories Staff for The Control of Cholera Epidemic In Al-Hilla City

Kufa Journal for Nursing Sciences, 2016
Background: Cholera is one of intestinal disease conceded life-threatening can spread rapidly of place to another and cause epidemic, affecting the population. The causative agent of cholera is gram-negative bacterium called Vibrio cholera. In 2015 Iraq
Amean A. Yasir, Haqi I. Mansoor
doaj   +1 more source

The Importance of Including Non-Household Environments in Dengue Vector Control Activities. [PDF]

Viruses, 2023
Peña-García VH, Mutuku FM, Ndenga BA, Mbakaya JO, Ndire SO, Agola GA, Mutuku PS, Malumbo SL, Ng'ang'a CM, Andrews JR, Mordecai EA, LaBeaud AD.   +11 more
europepmc   +1 more source

Policy based roles for distributed systems security

, 1997
Distributed systems are increasingly being used in commercial environments necessitating the development of trustworthy and reliable security mechanisms. There is often no clear informal or formal specification of enterprise authorisation policies and no
Lupu,E.C.,, Sloman,M.S.,, Yialelis,N.,
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The impact of agricultural activities on water quality: a case for collaborative catchment-scale management using integrated wireless sensor networks

, 2013
The challenge of improving water quality is a growing global concern, typified by the European Commission Water Framework Directive and the United States Clean Water Act.
Coles, Neil, Harris, Nick, Merrett, Geoff V., Rivers, Mark, Zia, Huma   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Control activities of notaries

RUDN Journal of Law, 2012
This article is devoted to analysis of the legislation of the Russian Federation, regulating the procedure the control of notarial acts, and to develop suggestions for their improvement.
E V Vinogradova, P A Vinogradova
doaj  

Implementation strategies preferred by primary care clinicians to facilitate cancer prevention and control activities. [PDF]

J Behav Med, 2023
Glasgow RE, Brtnikova M, Dickinson LM, Carroll JK, Studts JL.   +4 more
europepmc   +1 more source