Results 81 to 90 of about 2,215,651 (266)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Importance of Including Non-Household Environments in Dengue Vector Control Activities. [PDF]

Viruses, 2023
Peña-García VH, Mutuku FM, Ndenga BA, Mbakaya JO, Ndire SO, Agola GA, Mutuku PS, Malumbo SL, Ng'ang'a CM, Andrews JR, Mordecai EA, LaBeaud AD.   +11 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Optimizing Motor Coordination in Children with Developmental Coordination Disorder: Mini-Handball vs. Motor Skills Training

Sports
Children with Developmental Coordination Disorder (DCD) experience motor competence challenges that hinder their participation in physical activities and affect daily functioning.
Hurshida Bekmanova, Orifjon Saidmamatov, Jasurbek Jammatov, Taxirbek Salayev, Raximov Quvondiq, Shikhov Gayrat, Olga Vasconcelos, Rita Barros, Claúdia Sousa, Paula Rodrigues   +9 more
doaj   +1 more source

Projected cancer burden, challenges, and barriers to cancer prevention and control activities in the state of Telangana. [PDF]

PLoS One, 2023
Mahajan H, Reddy N, Devi NGM, Poli UR, Jayaram M, Tetali S, Murthy GVS, Telangana Cancer Control Study Group.   +7 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Control activities of notaries

RUDN Journal of Law, 2012
This article is devoted to analysis of the legislation of the Russian Federation, regulating the procedure the control of notarial acts, and to develop suggestions for their improvement.
E V Vinogradova, P A Vinogradova
doaj  

Implementation strategies preferred by primary care clinicians to facilitate cancer prevention and control activities. [PDF]

J Behav Med, 2023
Glasgow RE, Brtnikova M, Dickinson LM, Carroll JK, Studts JL.   +4 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source