Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Healthcare staff evaluation of an emergency department mental health room: a Virtual reality study. [PDF]
de Moraes Goulart F +4 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Next-Generation Vaccines Leveraging T Cell-Centric Design, Mucosal Immunity, and Trained Innate Immunity for Respiratory and Enteric Pathogens. [PDF]
Salam MA +5 more
europepmc +1 more source
Biomechanical Effects of the MIND&GAIT Exercise Program on Sit-to-Stand and Marching in Place Motor Coordination in Institutionalized Older Adults: Implications for Functional Stability. [PDF]
Mercê C +4 more
europepmc +1 more source
Redefining pandemic resilience: a roadmap for post-infectious syndrome preparedness and health system transformation. [PDF]
Schieffer B.
europepmc +1 more source
Detection of commercial crop weeds using machine learning algorithms. [PDF]
Ramesh P +5 more
europepmc +1 more source
The Risk from Reopening International Travel During a Disease X Pandemic: A Case Study of SARS-CoV-2. [PDF]
Taylor RA +6 more
europepmc +1 more source

