Results 61 to 70 of about 87,117 (268)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An Intranet of Things approach for adaptable control of behavioral and navigation-based experiments

open access: yeseLife
Investigators conducting behavioral experiments often need precise control over the timing of the delivery of stimuli to subjects and to collect precise times of subsequent behavioral responses. Furthermore, investigators want fine-tuned control over how
John C Bowler   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Quality Control in Small and Medium Enterprises: A Study of Present Challenges and Future Opportunities

open access: yesJournal of Applied Engineering and Technological Science
Quality control is a critical foundation for establishing effective and efficient systems across industries, but small and medium enterprises (SMEs) face unique challenges in implementing effective quality control due to resource constraints. This study
Dyah Lestari Widaningrum   +4 more
doaj   +1 more source

Neural Control and Adaptive Neural Forward Models for Insect-like, Energy-Efficient, and Adaptable Locomotion of Walking Machines

open access: yesFrontiers in Neural Circuits, 2013
Living creatures, like walking animals, have found fascinating solutions for the problem of locomotion control. Their movements show the impression of elegance including versatile, energy-efficient, and adaptable locomotion.
Poramate eManoonpong   +2 more
doaj   +1 more source

Quantum Transduction with Adaptive Control

open access: yesPhysical Review Letters, 2018
5 pages, 3 ...
Zhang, Mengzhen   +2 more
openaire   +4 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Towards Adaptive Access Control [PDF]

open access: yes, 2018
Access control systems are nowadays the first line of defence of modern IT systems. However, their effectiveness is often compromised by policy miscofigurations that can be exploited by insider threats. In this paper, we present an approach based on machine learning to refine attribute-based access control policies in order to reduce the risks of users
Luciano Argento   +4 more
openaire   +2 more sources

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