Results 101 to 110 of about 12,904,123 (301)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

An efficient ant colony system based on receding horizon control for the aircraft arrival sequencing and scheduling problem [PDF]

, 2010
The aircraft arrival sequencing and scheduling (ASS) problem is a salient problem in air traffic control (ATC), which proves to be nondeterministic polynomial (NP) hard.
Liu, O., Kaynak, O., Li, Y,, Ip, W.H., Zhan, Z.H., Kwok, S.K., Zhang, J.   +6 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

General predictive control an investigation of perceived limitations [PDF]

, 2012
Includes abstract.Includes bibliographical references.This dissertation investigates how GPC handles these difficulties and what modifications to the basic algorithm have been applied in the pursuit of stable, fast and efficient ...
Cecchini, Christopher Domenic
core   +1 more source

Robust PI speed tracking control for PMSM system based on convex optimization algorithm

, 2014
In order to optimize the speed-control performance of the permanent magnet synchronous motor (PMSM) driver system, a novel proportional-integral (PI) speed tracking control algorithm with convex optimization techniques is developed in this paper. Instead
Yang Yi, Xiaokang Sun, Zhang, Tianping, Sun, Xiaokang, Weixing Zheng, Yi, Yang (R17681), Tianping Zhang, Zheng, Wei Xing (R8901)   +7 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Iterative learning control: algorithm development and experimental benchmarking

, 2009
This thesis concerns the general area of experimental benchmarking of Iterative Learning Control (ILC) algorithms using two experimental facilities. ILC is an approach which is suitable for applications where the same task is executed repeatedly over the
Cai, Zhonglun
core   +1 more source

Design and analysis of takeoff and landing control algorithm for four-rocket boosting drone

Hangkong gongcheng jinzhan
Fixed wing UAV takes off and lands on the ground with high requirements，which limits the application and development of fixed wing aircraft. Therefore，a scheme of four-rocket boosting drone to realize short-range takeoff and landing process is proposed ...
TIAN Weili, YAN Zhaowu, LI Wen, JIA Dong
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Research on active electrohydraulic steering control of heavy duty articulated vehicles in coal mine based on yaw motion compensation

Meitan xuebao
Due to the use of lumbar folding steering for heavy-duty articulated vehicles in coal mines, the lateral stiffness is weak and the disturbance factors are complex, making it more difficult to operate and easily causing safety problems.
Zhiyong REN, Qin SHI, Yuan ZHAO, Lei ZHANG, Zhenhua HUANG   +4 more
doaj   +1 more source