Results 51 to 60 of about 22,969,801 (317)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Development of algorithms for effective control of process of testing induction motors by mutual load [PDF]

Омский научный вестник, 2019
The urgency of the development of energy-efficient electrical systems designed for testing induction machines is formulated. The necessity of automation of test stands in order to increase their reliability is noted. As research object selected scheme
V. V. Kharlamov, D. I. Popov
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Design criterion to select adequate control algorithm for electro-hydraulic actuator applied to rocket engine flexible nozzle thrust vector control under specific load [PDF]

FME Transactions, 2013
The paper presents the challenge of finding the best criterion in selecting adequate control algorithm for electro-hydraulic actuator with a defined load.
Nauparac Dragan B., Prsić Dragan H., Miloš Marko, Samardžić Marija, Isaković Jovan   +4 more
doaj  

Control algorithms for mobile agents [PDF]

, 2000
In dieser Abhandlung werden verschiedene Kontrollmechanismen für mobile Agenten vorgeschlagen. Kontrollmechanismen werden sowohl für das Auffinden als auch für die Terminierung und Waisenerkennung von mobilen Agenten verwendet. Wir beginnen mit der Diskussion von Kontrollmechanismen, die spezifisch für den Einsatz im Bereich der mobilen Agenten ...
openaire   +2 more sources

Process Control Algorithms for Microprocessors

IFAC Proceedings Volumes, 1979
Abstract Advanced methods for automatic control characterized by increased complexity of controller structure, better adjusted algorithms, the use of state and /or parameter estimation techniques and DDC with multivariable or self-tuning algorithms permit to improve substantially the performances of the process control.
A. Varga, V. Sima, Th. Popescu, C. Vasiliu   +3 more
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Revisiting the Control Systems of Autonomous Vehicles in the Agricultural Sector: A Systematic Literature Review

IEEE Access
The primary objective of this article is to systematically review and categorize the diverse control algorithms applied in autonomous vehicles within the agricultural sector from 2000 to 2023.
Vinayambika S. Bhat, Yong Wang
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Research on Time Constant Test of Thermocouples Based on QNN-PID Controller

Sensors
The aim of this study is to solve the problem of it being difficult to obtain quantitative step signals when testing the time constant of thermocouples using the laser excitation method, thereby restricting the accuracy and repeatability of the test of ...
Chenyang Xu, Xiaojian Hao, Pan Pei, Tong Wei, Shenxiang Feng   +4 more
doaj   +1 more source