Results 21 to 30 of about 6,728 (264)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
The municipal solid waste (MSW) of large cities, in particular in developing countries, is mainly disposed of in landfills (LFs), whose inadequate management generates the emission of greenhouse gases and the production of leachates with high ...
Patricia Torres Lozada +2 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
The construction sector is a great contributor to global warming both in new and existing buildings. Minimum energy buildings (MEBs) demand as little energy as possible, with an optimized architectural design, which includes passive solutions.
Sergio Gómez Melgar +3 more
doaj +1 more source
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
El papel del gobierno en el desarrollo económico The role of government in economic development
Este articulo trata de responder a la siguiente pregunta: ¿cuales han sido los efectos de la planeacion del desarrollo sobre las transformaciones economicas y sociales de los ultimos treinta años? De acuerdo con el autor, la principal concecuencia de las
Stiglitz Joseph E.
doaj
La toxicidad de las aguas residuales provenientes de empresas de procesamiento de productos cárnicos fue evaluada antes y después del tratamiento usando un reactor secuencial por lotes (SBR). Las pruebas de toxicidad fueron evaluadas mediante el análisis
Diana C. Rodríguez-Loaiza +2 more
doaj +1 more source
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source

