Results 181 to 190 of about 1,090,202 (336)

Push-pull-block framework for lycopene biosynthesis: a comprehensive review of metabolic engineering strategies in <i>Saccharomyces cerevisiae</i>. [PDF]

Front Bioeng Biotechnol
Garaad FD, Karaca H.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

"Biodegradable caterpillar inspired soft robotic systems for targeted therapeutic delivery with intelligent <i>in vivo</i> navigation". [PDF]

RSC Adv
Pothal P, Sharma R, Verma R, Kumar D, Mundlia P, Dhiman V, Bhadada SK, Goel H, Ranawat P, Barnwal RP, Singh G.   +10 more
europepmc   +1 more source

Analysis and Control of a Vapour Compression System with Internal Heat Exchanger

reservedThis Thesis has been carried out in the downline of a curricular internship at VIS Engineering. VIS is a consulting company providing advanced technology services for energy systems focusing on vapor compression cycle (VCC) systems.
TABANI, JACOPO
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Engineering Lung-on-a-chip microdevices for respiratory disease modelling and drug testing: A fit-for-purpose framework for design and translational validation. [PDF]

Biomed Microdevices
Cheong SY, Liew TIZ, Wong CK, Teng XX, Cha XY, Ng NC, Wong RS, Goh BH.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Strategies and applications for alleviating carbon catabolite repression. [PDF]

Synth Syst Biotechnol
Lu M, Ding H, Zhang H, Xu J, Meng R, Li Y, Zhang Z, Zheng P, Zhu Y, Sun J.   +9 more
europepmc   +1 more source

System and control engineering.

Bulletin of the Japanese Society of Prosthetics and Orthotics, 1993
SAITO, Yukio, HIGASHIHARA, Takanori
openaire   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source