Results 241 to 250 of about 217,841 (299)

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu   +10 more
wiley   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

open access: yesAdvanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang   +11 more
wiley   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

open access: yesAdvanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin   +13 more
wiley   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo   +9 more
wiley   +1 more source

Multivariate control charts: Control charts for calibration curves

Fresenius' Journal of Analytical Chemistry, 1994
The proposed multivariate control charts for p-dimensional vectors are an extension of the conventional control charts for one variable. The controlling quantity is the Mahalanobis distance of vector x from the central value vector x..: D=(x-x..)TĈ-1.(x-x..), where Ĉ is the covariance matrix estimate. The quantity D has Hotelling's T2 distribution.
Oto Mestek   +2 more
openaire   +1 more source

A Dispersion Control Chart

Communications in Statistics - Simulation and Computation, 2008
The study proposes a Shewhart-type control chart, namely Q chart, based on inter-quartile range, for monitoring changes (especially of moderate and large amounts which is major concern of Shewhart-type control charts) in process dispersion assuming normality of quality characteristic to be monitored. The design structure of Q chart is developed and its
openaire   +2 more sources

Clinical control charts

Australian Dental Journal, 1974
Abstract— Using a modified DMF index from existing data a method, based on the amount of treatment previously received, is demonstrated for constructing control charts for assessing the effectiveness of and for detecting trends in a school dental service.
openaire   +2 more sources

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