Results 41 to 50 of about 4,749,982 (303)

Mechanical properties of a degradable phosphate glass fibre reinforced polymer composite for internal fracture fixation [PDF]

open access: yes, 2010
NOTICE: this is the author’s version of a work that was accepted for publication in Materials Science and Engineering. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Brauer, DS, Kobayashi, HYLS, Russel, C
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Microelectronics Process Engineering at San Jose State University: A Manufacturing-Oriented Interdisciplinary Degree Program [PDF]

open access: yes, 2002
San Jose State University\u27s new interdisciplinary curriculum in Microelectronics Process Engineering is described. This baccalaureate program emphasizes hands-on thin-film fabrication experience, manufacturing methods such as statistical process ...
Allen, Emily   +5 more
core   +1 more source

Conceptual Engineering, Topics, Metasemantics, and Lack of Control [PDF]

open access: yes, 2020
Conceptual engineering is now a central topic in contemporary philosophy. Just 4-5 years ago it wasn’t. People were then engaged in the engineering of various philosophical concepts (in various sub-disciplines), but typically not self-consciously so. Qua
Cappelen, Herman
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Computer program for the design of toroidal transformers [PDF]

open access: yes, 1973
Program relieves designer of most of the computational details, while he maintains control over most engineering decisions. Number of specifications that must be supplied by user allows for considerable flexibility and for exercise of engineering ...
Dayton, J. A., Jr.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The anglocentric tendency in the history of information engineering [PDF]

open access: yes, 2017
This paper examines the anglocentric nature of much writing on the history of technology, taking as an example important research results from the first half of the last century published in German and Russian in the field of information engineering. By ‘
Bissell, Christopher
core  

Quantum control in infinite dimensions

open access: yes, 2003
Accurate control of quantum evolution is an essential requirement for quantum state engineering, laser chemistry, quantum information and quantum computing.
Ball   +7 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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