Results 131 to 140 of about 7,258,932 (365)

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

FedArtML: A Tool to Facilitate the Generation of Non-IID Datasets in a Controlled Way to Support Federated Learning Research

open access: yesIEEE Access
Federated Learning (FL) enables collaborative training of Machine Learning (ML) models across decentralized clients while preserving data privacy. One of the challenges that FL faces is when the clients’ data is not independent and identically ...
Daniel Mauricio Jimenez Gutierrez   +3 more
doaj   +1 more source

Structural controllability and management of cascading regime shifts [PDF]

open access: yesarXiv
Abrupt transitions in ecosystems can be interconnected, raising challenges for science and management in identifying sufficient interventions to prevent them or recover from undesirable shifts. Here we use principles of network controllability to explore how difficult it is to manage coupled regime shifts.
arxiv  

Infection control management strategy for operating room during COVID-19 pandemic. [PDF]

open access: yesAnn Transl Med, 2022
Dai Y   +8 more
europepmc   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Tools for distributed application management [PDF]

open access: yes, 1990
Distributed application management consists of monitoring and controlling an application as it executes in a distributed environment. It encompasses such activities as configuration, initialization, performance monitoring, resource scheduling, and ...
Birman, Kenneth P.   +3 more
core   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Adverse events following immunization surveillance on two types of enterovirus 71 vaccines: A real-world comparative study in China

open access: yesHuman Vaccines & Immunotherapeutics
To comprehensively assess the safety and difference of two types of EV71 vaccines: EV71-Vero, produced using Vero cells and EV71-H2, using human diploid cells.
Yiqing Zhu   +7 more
doaj   +1 more source

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