Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022 Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley +1 more source
Retracted: Cleaning Quality Control Management of Medical Equipment in Hospital Disinfection Supply Room Based on Smart Medicine. [PDF]
Comput Intell Neurosci, 2023 Intelligence And Neuroscience C.
europepmc +1 more source
Environmental management activities of an infrastructure development project: the case of Beris Dam, Malaysia [PDF]
, 2006 Development projects need to integrate environmental dimensions into project management functions to ensure successful implementation of environmental management and control practices throughout the development process.
Asyirah Abdul Rahim, +2 more
core
Problems In Air Traffic Management: VI. Interaction of Training-Entry Age with Intellectual and Personality Characteristics of Air Traffic Control Specialists [PDF]
, 1965 David K. Trites
openalex +1 more source
Management control of intangibles [PDF]
Portuguese Journal of Management Studies, 2008 This paper analyzes the importance of management control on the intangible elements considering its contribution for value creation. Some intangible evaluation models and methodologies are discussed, taking into consideration their utility. A new methodological framework that considers the objectives of management control as well as its applicability ...
openaire +1 more source
Management control bij waardemanagement [PDF]
Maandblad Voor Accountancy en Bedrijfseconomie, 2009 In deze periode waar bedrijfsprestaties en beurskoersen onder hoogspanning staan als gevolg van de kredietcrisis, zou prestatiemanagement hoog op de agenda moeten staan. Dit artikel gaat in op hoe het sturen op economische waarde (Value-based Management – VBM) in het management control systeem wordt ingebed.
openaire +3 more sources
Molecular Oncology, EarlyView.The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh +6 more
wiley +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022 Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls +9 more
wiley +1 more source
Infection control management strategy for operating room during COVID-19 pandemic. [PDF]
Ann Transl Med, 2022 Dai Y +8 more
europepmc +1 more source